The antioxidant system of the respiratory tract. The intracellular antioxidant protection in the respiratory tract (part 6)

Authors

  • A.E. Abaturov State Institution “Dnipropetrovsk Medical Academy of Ministry of Health of Ukraine”, Dnipro, Ukraine http://orcid.org/0000-0001-6291-5386
  • A.P. Volosovets Bogomolets National Medical University, Kyiv, Ukraine
  • T.P. Borysova State Institution “Dnipropetrovsk Medical Academy of Ministry of Health of Ukraine”, Dnipro, Ukraine

DOI:

https://doi.org/10.22141/2224-0551.12.2.2017.99780

Keywords:

antioxidant system, respiratory tract, intracellular antioxidant protection, review

Abstract

The literature review presents the current data about peroxiredoxin system in the functioning of the intracellular antioxidant protection in the respiratory tract. We present a model of the molecular structure of certain peroxiredoxins. The peroxiredoxin-dependent oxidation reactions, antiapoptotic action and other physiological effects of peroxiredoxins system are considered in detail. Model of the molecular structure and biological function of the antioxidant factors with an indirect effect (APEX nuclease 1/Ref-1) are described.

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References

Abaturov AE, Volosovets AP, Khudiakov AE. Antioxidant system of respiratory tract. Antioxidant effector in supraepithelial and extracellular area. Zdorovye rebenka. 2016;3(71):161-171. (in Russian).

Dyrkheyeva NS, Khodyreva SN, Lavrik OI. Multifunctional apurinic/ apyrimidinic endonuclease 1 in a human: role of addictive functions. Molekulyarnaya biologiya. 2007;41(3):450-66. (in Russian).

Kalinina EV, Chernov NN, Saprin AN. Role of thio-, peroxi- and glutaredoxin in cellular redox-related processes. Uspehi biologicheskoy himii. 2008;48:319-31. (in Russian).

Shuvayeva TM, Novoselov VI, Fesenko EE, Lipkin VM. Peroxiredoxins are a new family of antioxidant proteins. Bioorganicheskaya khimiya. 2009;35(5):581-96. (in Russian).

Fisher AB, Dodia C, Feinstein SI, Ho YS. Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2. J Lipid Res. 2005 Jun;46(6):1248-56. Epub 2005 Mar 16. doi: 10.1194/jlr.M400499-JLR200.

Nelson KJ, Knutson ST, Soito L, Klomsiri C, Poole LB, Fetrow JS. Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis. Proteins. 2011 Mar;79(3):947-64. doi: 10.1002/prot.22936. Epub 2010 Dec 22.

Barranco-Medina S, Lázaro JJ, Dietz KJ. The oligomeric conformation of peroxiredoxins links redox state to function. FEBS Lett. 2009 Jun 18;583(12):1809-16. doi: 10.1016/j.febslet.2009.05.029. Epub 2009 May 22.

Bhakat KK, Mantha AK, Mitra S. Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein. Antioxid Redox Signal. 2009 Mar;11(3):621-38. doi: 10.1089/ARS.2008.2198.

Busso CS, Lake MW, Izumi T. Posttranslational modification of mammalian AP endonuclease (APE1). Cell Mol Life Sci. 2010 Nov;67(21):3609-20. doi: 10.1007/s00018-010-0487-3. Epub 2010 Aug 14.

Kim WC, Berquist BR, Chohan M, Uy C, Wilson DM 3rd, Lee CH. Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1. J Mol Biol. 2011 Sep 2;411(5):960-71. doi: 10.1016/j.jmb.2011.06.050. Epub 2011 Jul 6.

Cao Z, Tavender TJ, Roszak AW, Cogdell RJ, Bulleid NJ. Crystal structure of reduced and of oxidized peroxiredoxin IV enzyme reveals a stable oxidized decamer and a non-disulfide-bonded intermediate in the catalytic cycle. J Biol Chem. 2011 Dec 9;286(49):42257-66. doi: 10.1074/jbc.M111.298810. Epub 2011 Oct 12.

Balakrishna S, Saravia J, Thevenot P, Ahlert T, Lominiki S, Dellinger B, Cormier SA. Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs. Part Fibre Toxicol. 2011 Mar 9;8:11. doi: 10.1186/1743-8977-8-11.

Georgiadis MM, Luo M, Gaur RK, Delaplane S, Li X, Kelley MR. Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease. Mutat Res. 2008 Aug 25;643(1-2):54-63. doi: 10.1016/j.mrfmmm.2008.04.008. Epub 2008 May 18.

Hall A, Karplus PA, Poole LB. Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J. 2009 May;276(9):2469-77. doi: 10.1111/j.1742-4658.2009.06985.x. Epub 2009 Mar 24.

Hansen JM, Moriarty-Craige S, Jones DP. Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kappaB activities. Free Radic Biol Med. 2008 Jul 15;43(2):282-8. Epub 2007 Apr 29. doi: 10.1016/j.freeradbiomed.2007.04.029.

Ishii T, Warabi E, Yanagawa T. Novel roles of peroxiredoxins in inflammation, cancer and innate immunity. J Clin Biochem Nutr. 2012 Mar;50(2):91-105. doi: 10.3164/jcbn.11-109. Epub 2012 Feb 18.

Kelley MR, Georgiadis MM, Fishel ML. APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1. Curr Mol Pharmacol. 2012 Jan;5(1):36-53. PMCID: PMC3319314.

Kim SY, Chun E, Lee KY. Phospholipase A(2) of peroxiredoxin 6 has a critical role in tumor necrosis factor-induced apoptosis. Cell Death Differ. 2011 Oct;18(10):1573-83. doi: 10.1038/cdd.2011.21. Epub 2011 Mar 18.

Knoops B, Goemaere J, Van der Eecken V, Declercq JP. Peroxiredoxin 5: structure, mechanism, and function of the mammalian atypical 2-Cys peroxiredoxin. Antioxid Redox Signal. 2011 Aug 1;15(3):817-29. doi: 10.1089/ars.2010.3584. Epub 2011 Apr 20.

Lowther WT, Haynes AC. Reduction of cysteine sulfinic acid in eukaryotic, typical 2-Cys peroxiredoxins by sulfiredoxin. Antioxid Redox Signal. 2011 Jul 1;15(1):99-109. doi: 10.1089/ars.2010.3564. Epub 2010 Dec 17.

Krutilina RI, Kropotov AV, Leutenegger C, Serikov VB. Migrating leukocytes are the source of peroxiredoxin V during inflammation in the airways. J Inflamm (Lond). 2006 Oct 4;3:13. doi: 10.1186/1476-9255-3-13.

Neumann CA, Cao J, Manevich Y. Peroxiredoxin 1 and its role in cell signaling. Cell Cycle. 2009 Dec 15;8(24):4072-8. Epub 2009 Dec 5. doi: 10.4161/cc.8.24.10242.

Rhee SG, Kang SW, Chang TS, Jeong W, Kim K. Peroxiredoxin, a novel family of peroxidases. IUBMB Life. 2001 Jul;52(1-2):35-41. doi: 10.1080/15216540252774748.

Park SY, Yu X, Ip C, Mohler JL, Bogner PN, Park YM. Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation. Cancer Res. 2007 Oct 1;67(19):9294-303. doi: 10.1158/0008-5472.CAN-07-0651.

Schremmer B, Manevich Y, Feinstein SI, Fisher AB. Peroxiredoxins in the lung with emphasis on peroxiredoxin VI. Subcell Biochem. 2007;44:317-44. PMID: 18084901.

Inoue K, Takano H, Koike E, Warabi E, Yanagawa T, Yanagisawa R, Ishii T. Peroxiredoxin I is a negative regulator of Th2-dominant allergic asthma. Int Immunopharmacol.2009 Oct;9(11):1281-8. doi: 10.1016/j.intimp.2009.07.010. Epub 2009 Aug 5.

Riddell JR, Wang XY, Minderman H, Gollnick SO. Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4. J Immunol. 2010 Jan 15;184(2):1022-30. doi: 10.4049/jimmunol.0901945. Epub 2009 Dec 16.

Chatterjee S, Feinstein SI, Dodia C, Sorokina E, Lien YC, Nguyen S, Debolt K, Speicher D, Fisher AB. Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages. J Biol Chem. 2011 Apr 1;286(13):11696-706. doi: 10.1074/jbc.M110.206623. Epub 2011 Jan 24.

Rhee SG, Woo HA, Kil IS, Bae SH. Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxides. J Biol Chem. 2012 Feb 10;287(7):4403-10. doi: 10.1074/jbc.R111.283432. Epub 2011 Dec 6.

Tae Lim Y, Sup Song D, Joon Won T, Lee YJ, Yoo JS, Eun Hyung K, Won Yoon J, Park SY, Woo Hwang K. Peroxiredoxin-1, a possible target in modulating inflammatory cytokine production in macrophage like cell line RAW264.7. Microbiol Immunol. 2012 Jun;56(6):411-9. doi: 10.1111/j.1348-0421.2012.00453.x.

Poole LB. The catalytic mechanism of peroxiredoxins/ In: Flohé L., Harris J.R., editors. Peroxiredoxin Systems. NY: Springer; 2007. 61-81.

Poole LB, Hall A, Nelson KJ. Overview of peroxiredoxins in oxidant defense and redox regulation. Curr Protoc Toxicol. 2011 Aug;Chapter 7:Unit7.9. doi: 10.1002/0471140856.tx0709s49.

Soito L, Williamson C, Knutson ST, Fetrow JS, Poole LB, Nelson KJ. PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family. Nucleic Acids Res. 2011 Jan;39:D332-7. doi: 10.1093/nar/gkq1060. Epub 2010 Oct 29.

Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med. 2005 Jun 15;38(12):1543-52. Epub 2005 Mar 24. doi: 10.1016/j.freeradbiomed.2005.02.026.

Rhee SG, Woo HA. Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H2O2, and protein chaperones. Antioxid Redox Signal. 2011 Aug 1;15(3):781-94. doi: 10.1089/ars.2010.3393. Epub 2011 Mar 31.

Yang D, Bai CX, Wang X, An XJ, Tong L, Bi J. Roles of peroxiredoxin 6 in the regulation of oxidative stress to lipopolysaccharide-induced acute lung injury. Zhonghua Jie He He Hu Xi Za Zhi. 2011 Sep;34(9):679-83. PMID: 22177494.

Hall A, Nelson K, Poole LB, Karplus PA. Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins. Antioxid Redox Signal. 2011 Aug 1;15(3):795-815. doi: 10.1089/ars.2010.3624. Epub 2011 Apr 20.

Tell G, Quadrifoglio F, Tiribelli C, Kelley MR. The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal. 2009 Mar;11(3):601-20. doi: 10.1089/ars.2008.2194.

Wood LG, Gibson PG, Garg ML. Biomarkers of lipid peroxidation, airway inflammation and asthma. Eur Respir J. 2003 Jan;21(1):177-86. PMID: 12570126.

Zhang Y, Wang J. Anticancer clinical utility of the apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1). Chin J Cancer. 2010 Mar;29(3):333-9. PMID: 20193121.

Published

2021-09-21

How to Cite

Abaturov, A., Volosovets, A., & Borysova, T. (2021). The antioxidant system of the respiratory tract. The intracellular antioxidant protection in the respiratory tract (part 6). CHILD`S HEALTH, 12(2), 193–199. https://doi.org/10.22141/2224-0551.12.2.2017.99780

Issue

Section

Theoretical Medicine

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