The Antioxidant System of the Respiratory Tract The Intracellular Antioxidant Protection in the Respiratory Tract (Part 2)

Authors

  • A.E. Abaturov State Institution «Dnipropetrovsk Medical Academy of Ministry of Healthcare of Ukraine», Dnipro, Ukraine http://orcid.org/0000-0001-6291-5386
  • A.P. Volosovets National Medical University named after O.O. Bohomolets, Kyiv, Ukraine
  • T.P. Borysova State Institution «Dnipropetrovsk Medical Academy of Ministry of Healthcare of Ukraine», Dnipro, Ukraine

DOI:

https://doi.org/10.22141/2224-0551.6.74.2016.82144

Keywords:

antioxidant system, respiratory tract, intracellular antioxidant protection

Abstract

The literature review presents the current data about the enzyme of intracellular antioxidant protection in the respiratory tract — catalase. The characteristics of catalase is presented and its functioning is described. Inactivation of hydrogen peroxide and secondary radicals, selenium-dependent molecular antioxidant systems are considered. The article details the glutathione system — its structure, content in the respiratory tract, metabolism.

Downloads

Download data is not yet available.

References

Vladimirov Yu.A. Zachem nuzhna belkovaya kristallografiya // Priroda. – 2003. - № 11. – S. 26-34.

Kostyuk V.A. Bioradikaly i bioantioksidanty / V.A. Kostyuk. A.I. Potapovich. – Minsk: BGU. 2004. – 174 s.

Moskalev A. A. Stareniye i geny. — SPb.: Nauka. 2008. — 358 s.

Chesnokova N.P. Molekulyarno-kletochnyye mekhanizmy inaktivatsii svobodnykh radikalov v biologicheskikh sistemakh/ N.P. Chesnokova. E.V. Ponukalina. M.N. Bizenkova // Uspekhi sovremennogo estestvoznaniya. – 2006. - № 7.- C 29-36.

Fitzpatrick AM, Teague WG, Holguin F, Yeh M, Brown LA; Severe Asthma Research Program. Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress.J Allergy Clin Immunol. 2009 Jan;123(1):146-152.e8. doi: 10.1016/j.jaci.2008.10.047.

Biswas SK, Rahman I. Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med. 2009 Feb-Apr;30(1-2):60-76. doi: 10.1016/j.mam.2008.07.001. Epub 2008 Aug 8.

Turanov AA, Xu XM, Carlson BA, Yoo MH, Gladyshev VN, Hatfield DL. Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis. Adv Nutr. 2011 Mar;2(2):122-8. doi: 10.3945/an.110.000265. Epub 2011 Mar 10.

Cooper AJ, Pinto JT, Callery PS. Reversible and irreversible protein glutathionylation: biological and clinical aspects. Expert Opin Drug Metab Toxicol. 2011 Jul;7(7):891-910. doi: 10.1517/17425255.2011.577738. Epub 2011 May 11.

Deneke SM. Thiol-based antioxidants. Curr Top Cell Regul. 2000;36:151-80. PMID: 10842751.

Jones DP1, Park Y, Gletsu-Miller N, Liang Y, Yu T, Accardi CJ, Ziegler TR. Dietary sulfur amino acid effects on fasting plasma cysteine/cystine redox potential in humans. Nutrition. 2011 Feb;27(2):199-205. doi: 10.1016/j.nut.2010.01.014. Epub 2010 May 14.

Forman HJ, Zhang H, Rinna A. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009 Feb-Apr;30(1-2):1-12. doi: 10.1016/j.mam.2008.08.006. Epub 2008 Aug 30.

Giordano G1, White CC, Costa LG. Assessment of glutathione homeostasis. Methods Mol Biol. 2011;758:205-14. doi: 10.1007/978-1-61779-170-3_14.

Rahman I1, Biswas SK, Jimenez LA, Torres M, Forman HJ.

Glutathione, stress responses, and redox signaling in lung inflammation. Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):42-59. doi: 10.1089/ars.2005.7.42

Noctor G, Queval G, Mhamdi A, Chaouch S, Foyer CH. Glutathione. Arabidopsis Book. 2011;9:e0142. doi: 10.1199/tab.0142. Epub 2011 Feb 18.

Goyal MM, Basak A. Human catalase: looking for complete identity. Protein Cell. 2010 Oct;1(10):888-97. doi: 10.1007/s13238-010-0113-z. Epub 2010 Nov 9.

Hawkes WC, Alkan Z. Regulation of redox signaling by selenoproteins. Biol Trace Elem Res. 2010 Jun;134(3):235-51. doi: 10.1007/s12011-010-8656-7. Epub 2010 Mar 20.

Holmgren A, Sengupta R. The use of thiols by ribonucleotide reductase. Free Radic Biol Med. 2010 Dec 1;49(11):1617-28. doi: 10.1016/j.freeradbiomed.2010.09.005. Epub 2010 Sep 16.

Hondal RJ, Ruggles EL. Differing views of the role of selenium in thioredoxin reductase. Amino Acids. 2011 Jun;41(1):73-89. doi: 10.1007/s00726-010-0494-6. Epub 2010 Feb 21.

Jones DP, Go YM. Redox compartmentalization and cellular stress. Diabetes Obes Metab. 2010 Oct;12 Suppl 2:116-25. doi: 10.1111/j.1463-1326.2010.01266.x.

Joyce-Brady M, Hiratake J. Inhibiting Glutathione Metabolism in Lung Lining Fluid as a Strategy to Augment Antioxidant Defense.Curr Enzym Inhib. 2011 Jul;7(2):71-78. doi: 10.2174/157340811796575308.

Kaarteenaho-Wiik R, Kinnula VL. Distribution of antioxidant enzymes in developing human lung, respiratory distress syndrome, and bronchopulmonary dysplasia. J Histochem Cytochem. 2004 Sep;52(9):1231-40. doi: 10.1369/jhc.4A6291.2004.

Keppler D. Multidrug resistance proteins (MRPs, ABCCs): importance for pathophysiology and drug therapy. Handb Exp Pharmacol. 2011;(201):299-323. doi: 10.1007/978-3-642-14541-4_8.

Koháryová M, Kolárová M. Oxidative stress and thioredoxin system. Gen Physiol Biophys. 2008 Jun;27(2):71-84. PMID: 18645221.

Lu J, Holmgren A. Selenoproteins. J Biol Chem. 2009 Jan 9;284(2):723-7. doi: 10.1074/jbc.R800045200. Epub 2008 Aug 29.

Lushchak VI. Glutathione homeostasis and functions: potential targets for medical interventions. J Amino Acids. 2012;2012:736837. doi: 10.1155/2012/736837. Epub 2012 Feb 28.

Vlasits J, Jakopitsch C, Bernroitner M, Zamocky M, Furtmüller PG, Obinger C. Mechanisms of catalase activity of heme peroxidases.Arch Biochem Biophys. 2010 Aug 1;500(1):74-81. doi: 10.1016/j.abb.2010.04.018. Epub 2010 Apr 29.

Marí M, Morales A, Colell A, García-Ruiz C, Fernández-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009 Nov;11(11):2685-700. doi: 10.1089/ARS.2009.2695.

Zámocký M, Gasselhuber B, Furtmüller PG, Obinger C. Molecular evolution of hydrogen peroxide degrading enzymes. Arch Biochem Biophys. 2012 Sep 15;525(2):131-44. doi: 10.1016/j.abb.2012.01.017. Epub 2012 Feb 7.

Ballatori N, Krance SM, Marchan R, Hammond CL. Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology. Mol Aspects Med. 2009 Feb-Apr;30(1-2):13-28. doi: 10.1016/j.mam.2008.08.004. Epub 2008 Aug 26.

Rahman I, Biswas SK, Kode A. Oxidant and antioxidant balance in the airways and airway diseases.Eur J Pharmacol. 2006 Mar 8;533(1-3):222-39. Epub 2006 Feb 28. doi: 10.1016/j.ejphar.2005.12.087

Kumar A, Farhana A, Guidry L, Saini V, Hondalus M, Steyn AJ. Redox homeostasis in mycobacteria: the key to tuberculosis control? Expert Rev Mol Med. 2011 Dec 16;13:e39. doi: 10.1017/S1462399411002079.

Reeves MA, Hoffmann PR.The human selenoproteome: recent insights into functions and regulation.Cell Mol Life Sci. 2009 Aug;66(15):2457-78. doi: 10.1007/s00018-009-0032-4. Epub 2009 Apr 28.

Reynaert NL. Glutathione biochemistry in asthma.Biochim Biophys Acta. 2011 Nov;1810(11):1045-51. doi: 10.1016/j.bbagen.2011.01.010. Epub 2011 Jan 31.

Scibior D, Czeczot H. [Catalase: structure, properties, functions]. [Article in Polish] Postepy Hig Med Dosw (Online). 2006;60:170-80. PMID: 16618987.

Xiong Y, Uys JD, Tew KD, Townsend DM. S-glutathionylation: from molecular mechanisms to health outcomes. Antioxid Redox Signal. 2011 Jul 1;15(1):233-70. doi: 10.1089/ars.2010.3540. Epub 2011 May 25.

Nakamura H, Hoshino Y, Okuyama H, Matsuo Y, Yodoi J. Thioredoxin 1 delivery as new therapeutics.Adv Drug Deliv Rev. 2009 Apr 28;61(4):303-9. PMID: 19385090.

Townsend DM, Tew KD, Tapiero H. The importance of glutathione in human disease. Biomed Pharmacother. 2003 May-Jun;57(3-4):145-55. PMID:12818476.

Wouters MA, Fan SW, Haworth NL. Disulfides as redox switches: from molecular mechanisms to functional significance. Antioxid Redox Signal. 2010 Jan;12(1):53-91. doi: 10.1089/ARS.2009.2510.

Zámocký M, Koller F.Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis. Prog Biophys Mol Biol. 1999;72(1):19-66.PMID:10446501.

http://en.wikipedia.org/wiki/File:PDB_7cat_EBI.jpg

Published

2021-09-21

How to Cite

Abaturov, A., Volosovets, A., & Borysova, T. (2021). The Antioxidant System of the Respiratory Tract The Intracellular Antioxidant Protection in the Respiratory Tract (Part 2). CHILD`S HEALTH, (6.74), 121–127. https://doi.org/10.22141/2224-0551.6.74.2016.82144

Issue

Section

Theoretical Medicine

Most read articles by the same author(s)

<< < 8 9 10 11 12 13 14 > >>