Frequency of detection of allergic reactions to food in children with atopic dermatitis and pathology of the gastrointestinal tract

Authors

  • T.O. Kryuchko Ukrainian Medical Stomatological Academy, Poltava, Ukraine
  • L.M. Bubyr Ukrainian Medical Stomatological Academy, Poltava, Ukraine
  • I.M. Nesina Ukrainian Medical Stomatological Academy, Poltava, Ukraine
  • O.Ya. Tkachenko Ukrainian Medical Stomatological Academy, Poltava, Ukraine http://orcid.org/0000-0002-0789-5340

DOI:

https://doi.org/10.22141/2224-0551.14.4.2019.174031

Keywords:

children, food allergy, food hypersensitivity, causative allergens, atopy

Abstract

Background. In recent years, there has been a worldwide tendency to steady increase in the incidence of adverse reactions caused by food. Therefore, at the present stage, the investigation of the prevalence of the main causative factors of the development of food hypersensitivity is still a challenging task for researchers. The purpose was to study the range of food products, which are the most likely allergy-causing for children of the Poltava region, who had a history of unwanted allergic reactions to food. Materials and methods. The study involved 242 children aged from 6 to 15 years, who had a history about adverse reactions caused by food. The basic group included 128 patients with inflammatory diseases of the upper gastrointestinal tract; the comparison group involved 114 children with atopic dermatitis. The detection of the frequency of allergic reactions to food was investigated by using a questionnaire, allergic anamnesis and findings obtained by skin prick tests with food, epidermal, household and pollen allergens. Results. The study has demonstrated that the factors significantly increasing risks of skin and gastrointestinal allergies in the examined children are as following: maternal hereditary burden of allergic diseases; non-compliance in pregnancy, when mothers of examined children neglected to stick to the hypoallergenic diet; early mixed and bottle feeding and improper introducing of solid food. The findings obtained by questionnaire and skin allergic tests demonstrated a higher level of food sensitization in the children of the basic group. It has been also found out that the development of adverse reactions, regardless of skin or gastrointestinal manifestations, is the most often observed when taking cow’s milk, eggs and fish. Conclusions. Thus, the conducted studies have contributed in finding out main risk factors for the development of food hypersensitivity in children and in identifying the most etiologically significant food products that can provoke the development of allergic and gastroenterological diseases.

Downloads

Download data is not yet available.

References

Muraro A, Halken S, Arshad SH, et al. EAACI food allergy and anaphylaxis guidelines. Primary prevention of food allergy. Allergy. 2014 May;69(5):590-601. doi: 10.1111/all.12398.

Kajdashev IP. Review of adverse food reactions. Klinichna immunolohiia. Alerholohiia. Infektolohiia. 2018;(1):5-12. (in Russian).

Miles EA, Calder PC. Maternal diet and its influence on the development of allergic disease. Clin Exp Allergy. 2015 Jan;45(1):63-74. doi: 10.1111/cea.12453.

Makarova SG, Namazova-Baranova LS, Vishneva EA, Gevorkyan AK, Alekseeva AA, Petrovskaya MI. Topical issues of food allergy diagnosis in pediatric practice. Vestnik Rossiiskoi akademii meditsinskikh nauk. 2015;70(1):41-46. (in Russian).

Zajkov SV. Food intolerance and food allergies in children. Dytiachyi likar. 2011;(3):38-45. (in Ukrainian).

Sicherer SH, Allen K, Lack G, Taylor SL, Donovan SM, Oria M. Critical Issues in Food Allergy: A National Academies Consensus Report. Pediatrics. 2017 Aug;140(2). pii: e20170194. doi: 10.1542/peds.2017-0194.

Tkachenko OYa. Food allergy in children as a key link in the realization of atopy. Neonatology, surgery and perinatal medicine. 2014;4(11):106-113. (in Ukrainian).

Munblit D, Boix-Amoros A, Boyle RJ, et al. Human milk and allergic diseases: Unsolved puzzle. Nutrients. 2017 Aug 17;9(8). pii: E894. doi: 10.3390/nu9080894.

Kryuchko TO, Nesina IM, Tkachenkо OYa. Diagnostic algorithm and peculiarities of monitoring for infants with disorders of the gastrointestinal tract. Wiadomości Lekarskie. 2017;70;(2):275-282.

Abaturov O, Dytiatkovsky V, Naumenko N, Kulieva A, Bovsunovska K, Filatova I. Association between atopic and non-atopic diseases at children. Medicni perspektivi. 2018;23;(1-1):146-153.

Published

2021-09-10

How to Cite

Kryuchko, T., Bubyr, L., Nesina, I., & Tkachenko, O. (2021). Frequency of detection of allergic reactions to food in children with atopic dermatitis and pathology of the gastrointestinal tract. CHILD`S HEALTH, 14(4), 199–204. https://doi.org/10.22141/2224-0551.14.4.2019.174031

Issue

Section

Clinical Pediatrics

Most read articles by the same author(s)

1 2 3 > >>