Drugs inhibiting the quorum-sensing of bacteria Staphylococcus aureus


  • А.Е. Abaturov State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine http://orcid.org/0000-0001-6291-5386
  • Т.А. Kryuchko Ukrainian Medical Stomatological Academy, Poltava, Ukraine




quorum sensing, Staphylococcus aureus, inhibitors of quorum sensing, review


The scientific review presents data on the functioning of the quorum-sensing systems Agr and RAP/TRAP of Staphylococcus aureus bacteria. The paper gives the characteristics of medications inhibiting the export of AIP from a bacterial cell, the activity of histidine kinase AgrC, the expression and functional activity of AgrA, the expression of the RNAIII transcript of Staphylococcus aureus bacteria. It is suggested that the drugs developed to inhibit the activity of the mechanisms of the quorum sensing of Staphylococcus aureus bacteria will take a worthy place in anti-staphylococcal therapy.


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How to Cite

Abaturov А., & Kryuchko Т. (2021). Drugs inhibiting the quorum-sensing of bacteria Staphylococcus aureus. CHILD`S HEALTH, 14(3), 189–198. https://doi.org/10.22141/2224-0551.14.3.2019.168803



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