The Role of DNA sensors in Recognition of Pathogen-associated Molecular Patterns of Infectious Agents and the Development of Inflammation. Part 1. Z-DNA-binding Proteins Family

A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish

Abstract


The survey characterized molecular family of Z-DNA-binding proteins and their role in the development of infectious process.

Keywords


inflammation; infectious process; DNA sensors

References


Ablasser A., Hornung V. DNA sensing unchained // Cell. Res. — 2013. — Vol. 23, № 5. — P. 585-587.

Crystal structure of a junction between two Z-DNA helices / M. de Rosa, D. de Sanctis, A.L. Rosario, M. Archer, A. Rich, A. Athanasiadis, M.A. Carrondo // Proc. Natl. Acad. Sci. USA. — 2010. — Vol. 107, № 20. — P. 9088-9092.

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response / A. Takaoka, Z. Wang, M.K. Choi, H. Yanai, H. Negishi, T. Ban, Y. Lu, M. Miyagishi, T. Kodama, K. Honda, Y. Ohba, T. Taniguchi // Nature. — 2007. — Vol. 448, № 7152. — P. 501-505.

Deigendesch N., Koch-Nolte F., Rothenburg S. ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains // Nucleic Acids Res. — 2006. — Vol. 34, № 18. — P. 5007-5020.

Farajollahi S., Maas S. Molecular diversity through RNA editing: a balancing act // Trends Genet. — 2010. — Vol. 26, № 5. — P. 221-230.

Gene-targeted mice lacking the Trex1 (DNase III) 3`→5` DNA exonuclease develop inflammatory myocarditis / M. Morita, G. Stamp, P. Robins, A. Dulic, I. Rosewell, G. Hrivnak, G. Daly, T. Lindahl, D.E. Barnes // Mol. Cell. Biol. — 2004. — Vol. 24, № 15. — P. 6719-6727.

Herbert A., Rich A. The biology of left-handed Z-DNA // J. Biol. Chem. — 1996. — Vol. 271, № 20. — P. 11595-11598.

Host innate immune receptors and beyond: making sense of microbial infections / K.J. Ishii, S. Koyama, A. Nakagawa, C. Coban, S. Akira // Cell Host. Microbe. — 2008. — Vol. 3, № 6. — P. 352-363.

Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1 / V.R. DeFilippis, D. Alvarado, T. Sali, S. Rothenburg, K. Früh // J. Virol. — 2010. — Vol. 84, № 1. — P. 585-598.

Innate recognition of bacteria by a macrophage cytosolic surveillance pathway / M. O’Riordan, C.H. Yi, R. Gonzales, K.D. Lee, D.A. Portnoy // Proc. Natl. Acad. Sci. U. S. A. — 2002. — Vol. 99, № 21. — P. 3861-13866.

Kaiser W.J., Upton J.W., Mocarski E.S. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kB activation via the DNA-dependent activator of IFN regulatory factors // J. Immunol. — 2008. — Vol. 181, № 9. — P. 6427-6434.

Kypr J., Kejnovská I., Renciuk D., Vorlícková M. Circular dichroism and conformational polymorphism of DNA // Nucleic Acids Res. — 2009. — Vol. 37, № 6. — P. 1713-1725.

Molecular cloning and functional characterization of porcine DNA-dependent activator of IFN-regulatory factors (DAI) / L. Xie, L. Fang, D. Wang, R. Luo, K. Cai, H. Chen, S. Xiao // Dev. Comp. Immunol. — 2010. — Vol. 34, № 3. — P. 293-299.

New roles for the major human 3'-5' exonuclease TREX1 in human disease / D. Kavanagh, D. Spitzer, P.H. Kothari, A. Shaikh, M.K. Liszewski, A. Richards, J.P. Atkinson // Cell Cycle. — 2008. — Vol. 7, № 12. — P. 1718-1725.

Nie Y., Hammond G. L., Yang J.-H. Double-Stranded RNA Deaminase ADAR1 Increases Host Susceptibility to Virus Infection // J. Virol. — 2007. — Vol. 81, № 2. — Р. 917-923.

p150 ADAR1 isoform inVolved in maintenance of HeLa cell proliferation / H. Wang, Z. Hou, Y. Wu, X. Ma, X. Luo // BMC Cancer. — 2006. —Vol. 6, № 1. — P. 282.

Phan A.T., Kuryavyi V., Patel D.J. DNA architecture: from G to Z // Curr. Opin. Struct. Biol. — 2006. — Vol. 16, № 3. — P. 288-298.

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules / Z. Wang, M.K. Choi, T. Ban, H. Yanai, H. Negishi, Y. Lu, T. Tamura, A. Takaoka, K. Nishikura, T. Taniguchi // Proc. Natl. Acad. Sci. USA. — 2008. — Vol. 105, № 14. — P. 5477-5482.

Rothenburg S., Schwartz T., Koch-Nolte F., Haag F. Complex regulation of the human gene for the Z-DNA binding protein DLM-1 // Nucleic Acids Res. — 2002. — Vol. 30, № 4. — P. 993-1000.

Stetson D.B., Medzhitov R. Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune Response // Immunity. — 2006. — Vol. 24, № 1. — P. 93-103.

Stetson D.B., Ko J.S., Heidmann T., Medzhitov R. Trex1 prevents cell-intrinsic initiation of autoimmunity // Cell. — 2008. — Vol. 134, № 4. — P. 587-598.

Takaoka A., Shinohara S . DNA sensors in innate immune system / Uirusu. — 2008 — Vol. 58, № 1. — P. 37-46.

Takaoka A., Taniguchi T. Cytosolic DNA recognition for triggering innate immune responses // Adv. Drug. Deliv. Rev. — 2008. — Vol. 60, № 7. — P. 847-857.

Takeuchi O., Akira S. Pattern recognition receptors and inflammation // Cell. — 2010. — Vol. 140, № 6. — P. 805-820.

The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease / D.A. Lehtinen, S. Harvey, M.J. Mulcahy, T. Hollis, F.W. Perrino // J. Biol. Chem. — 2008. — Vol. 283, № 46. — P. 31649-31656.

Theofilopoulos A.N., Kono D.H., Beutler B., Baccala R. Intracellular nucleic acid sensors and autoimmunity // J. Interferon Cytokine Res. — 2011. — Vol. 31, № 12. — P. 867-886.

Vilaysane A., Muruve D. A. The innate immune response to DNA // Sem. Immunol. — 2009. — Vol. 21, № 4. — P. 208-214.

Wells R.D. Non-B DNA conformations, mutagenesis and disease // Trends Biochem. Sci. — 2007. — Vol. 32, № 8. — P. 271-278.

Wilkins C., Gale M. Jr. Recognition of viruses by cytoplasmic sensors // Curr. Opin. Immunol. — 2010. — Vol. 22, № 1. — P. 41-47.

Wong S.K., Lazinski D.W. Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1 // Proc. Natl. Acad. Sci. U.S.A. — 2002. — Vol. 99, № 23. — P. 15118-15123.

Yanai H., Savitsky D., Tamura T., Taniguchi T. Regulation of the cytosolic DNA-sensing system in innate immunity: a current view // Curr. Opin. Immunol. — 2009. — Vol. 21, № 1. — P. 17-22.

Yang H., Young D. W., Gusovsky F., Chow J. C. Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1 // J. Biol. Chem. — 2000. — Vol. 275, № 27. — P. 20861-20866.

Z-DNA binding proteins as targets for structure-based virtual screening / D. Kim, Y.H. Lee, H.Y. Hwang, K.K. Kim, H.J. Park // Curr. Drug Targets. — 2010. — Vol. 11, № 3. — P. 335-344.




DOI: https://doi.org/10.22141/2224-0551.8.51.2013.85117

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