Risk Factors for Pathology of the Upper Gastrointestinal Tract in Children with Bronchial Asthma

Yu.K. Bolbot, M.V. Kalichevska


Objective: to create a model for predicting the risk of upper gastrointestinal diseases in children with bronchial asthma.
Material and Methods. The study included 120 children with bronchial asthma, 78 of them had concomitant pathology of the upper gastrointestinal tract. All children underwent general clinical, laboratory and instrumental examination. Based on the analysis of primary medical records (patient’s medical card (F-003/o) and child’s records (F-112)), we have evaluated retrospectively the data of ante-, peri- and postnatal periods, clinical manifestations of atopy and concomitant somatic pathology.
Results. In terms of the regression analysis, there were determined risk factors for chronic gastroduodenal pathology in children with bronchial asthma: child’s sex, disease duration, severity of asthma symptoms and level of their control, as well as duration of breastfeeding, food sensitization, H.pylori infection, the presence of digestive pathology in child’s parents. Several models for predicting the risk of chronic diseases of the upper gastrointestinal tract (including destructive ones) in this group of patients were developed, based on clinical and laboratory parameters. These prognostic models have a sufficient level of sensitivity, easy to use and can be recommended for primary care physicians.


children; bronchial asthma; pathology of upper gastrointestinal tract; risk factors


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DOI: https://doi.org/10.22141/2224-0551.


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