Project of the Modern Classification of the Food Hypersensitivity Clinical Symptoms in Сhildren
Actuality. Food hypersensitivity (FH) remains an important problem of the childhood that has medical and social sides. For the decades, classification of FH skin manifestations is based on the combination of not clear pathophysiological and clinical signs and is caused by insufficient use of the method of morphological determination of rash elements and its comparison with a past medical history. Objective. To propose updated definitions and the project of classification of clinical manifestations of food hypersensitivity that will enable to improve clinical significance, to identify targets of possible therapeutic intervention at different pathogenetic mechanisms of FH, to increase the efficacy of clinical diagnostics, to develop common approaches to the data interpretation. Materials and methods. Advanced review of the literature sources, both paper and electronic (including Medline and the Cochrane Library, 2010–2016), as well as the results of own researches served as the basis for the creation of the project. Results. The current classification of FH is ambiguous and reflects the lack of understanding of the nature of the disease, which may have immune and non-immune mechanisms. Problems with verifying the diagnosis are also due to the fact that the same symptom in the skin can occur at different pathophysiological mechanisms of development, that is why it is important to take into account anamnesis and subjective symptoms, which differ in specific forms of FH. The article offers the draft classification of clinical manifestations of FH, based on recent literature data and the results of own observations. Target organ and pathogenetic mechanism, some morphological elements are taken as the basis. Conclusions. The proposed method will improve the clinical significance and make it possible to create a unified approach to the data interpretation.
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Abek D, Burgdorf V, Kremer X. [Skin diseases in children]. Moskow: Med lit; 2007. 160p. Russian.
Chop'yak VV, Golovin RR, Nasadyuk XM. [Food allergy]. Kly`ny`cheskaya y`mmunology`ya. Allergology`ya. Y`nfektology`ya. 2010;5-6:34-35. Ukranian.
Eigenmann PA, Beyer K, Wesley Burks A, Lack G, Liacouras CA, Hourihane JO, Sampson HA, Sodergren E.New visions for food allergy: an iPAC summary and future trends. Pediatr Allergy Immunol. 2008 Aug;19 Suppl 19:26-39. doi: 10.1111/j.1399-3038.2008.00765.x.
Fiocchi A, Schünemann HJ, Brozek J, Restani P, Beyer K, Troncone R, Martelli A, Terracciano L, Bahna SL, Rancé F, Ebisawa M, Heine RG, Assa'ad A, Sampson H, Verduci E, Bouygue GR, Baena-Cagnani C, Canonica W, Lockey RF. Diagnosis and Rationale for Action Against Cow's Milk Allergy (DRACMA): a summary report. J Allergy Clin Immunol. 2010 Dec;126(6):1119-28.e12. doi: 10.1016/j.jaci.2010.10.011.
Heratizadeh A, Wichmann K, Werfel T. Food allergy and atopic dermatitis: how are they connected? Curr Allergy Asthma Rep. 2011;Aug;11(4):284-91. doi: 10.1007/s11882-011-0202-y.
Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, Motala C, Ortega Martell JA, Platts-Mills TA, Ring J, Thien F, Van Cauwenberge P, Williams HC. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol. 2004; May;113(5):832-6.
Joshua A. Boyce, MD, Amal Assa'ad, MD, A. Wesley Burks et al. Guidelines for the Diagnosis and Management of Food Allergy in the United States. Summary of the NIAID-Sponsored Expert Panel Report. J Allergy Clin Immunol. 2010 Dec; 126(6): 1105–1118. doi: 10.1016/j.jaci.2010.10.008.
Kly`menko VA, Ashheulov AM, Sy`ndeeva NT. [Clinical case of the Heiner syndrome]. Zdorov`e rebenka. 2014;5:130-133. Russian.
Muraro A, Werfel T, Hoffmann-Sommergruber K, Roberts G, Beyer K, Bindslev-Jensen C, Cardona V, Dubois A, duToit G, Eigenmann P, Fernandez Rivas M, Halken S, Hickstein L, Høst A, Knol E, Lack G, Marchisotto MJ, Niggemann B, Nwaru BI, Papadopoulos NG, Poulsen LK, Santos AF, Skypala I, Schoepfer A, Van Ree R, Venter C, Worm M, Vlieg-Boerstra B, Panesar S, de Silva D, Soares-Weiser K, Sheikh A, Ballmer-Weber BK, Nilsson C, de Jong NW, Akdis CA; EAACI Food Allergy and Anaphylaxis Guidelines Group. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy. Allergy. 2014 Aug;69(8):1008-25. doi: 10.1111/all.12429.
Nedel`skaya SN, Paxol`chuk OP. [Difficulties and mistakes or how authorized is diagnosis ”food allergy”]. Zaporozh. med. Zhurn. 2014;N 1: 104-106. Russian.
Nedelska SN, Pakholchuk OP. An 8-month old with erythema nodosum - clinical case report. Patologiya : Naukovo-prakty`chny`j medy`chny`j zhurnal. 2015; N 2:114-116. English.
Nwaru BI, Hickstein L, Panesar SS, Muraro A, Werfel T, Cardona V, Dubois AE, Halken S, Hoffmann-Sommergruber K, Poulsen LK, Roberts G, Van Ree R, Vlieg-Boerstra BJ, Sheikh A. The epidemiology of food allergy in Europe: a systematic review and meta-analysis; EAACI Food Allergy and Anaphylaxis Guidelines Group. Allergy. 2014;Jan;69(1):62-75. doi: 10.1111/all.12305.
Pakholchuk OP. [Features of the clinical food allergy skin manifestations verification in children]. Visny`k problem biologiyi i medy`cy`ny`. 2015;2,Т.3 (120):212-215. Ukranian.
Prescot S. FA: riding the second wave of the allergy epidemic. Pediatr Allergy Immunol. 2011;22:155-160.
Scheller JM. The history, epidemiology, and classification of headaches in childhood. / Semin Pediatr Neurol. 1995 Jun;2(2):102-8.
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