Asymptomatic Hyperamylasemia in the Onset of Inflammatory Bowel Diseases in Children: A Case Report

Main Article Content

N.Yu. Zavhorodnya
O.Yu. Lukyanenko


The article analyzed the literature data on the epidemiology, etiology, mechanisms of pancreatic lesions in inflammatory bowel diseases in children. Range of pathological conditions of the pancreas in patients with inflammatory bowel diseases was considered. The algorithm for the differential diagnosis of asymptomatic increase of pancreatic enzymes in children was presented. A detailed analysis of clinical and anamnestic, laboratory and instrumental data has been performed, the diagnostic search algorithm in a boy with asymptomatic hyperamylasemia and ulcerative colitis was demonstrated.

Article Details

How to Cite
Zavhorodnya, N., and O. Lukyanenko. “Asymptomatic Hyperamylasemia in the Onset of Inflammatory Bowel Diseases in Children: A Case Report”. CHILD`S HEALTH, no., Oct. 2016, pp. 125-9, doi:10.22141/2224-0551.
Clinical Pediatrics


Bokemeyer B. Asymptomaticelevationof serum lipase and amylase in conjunction with Crohn's disease and ulcerative colitis / Bokemeyer B. // Z Gastroenterol. — 2002. — ​Vol. 40, № 1. — ​Р. 5-10. doi: 10.1055/s‑2002-19636.

CT and MRI of Rare Extraintestinal Manifestations of Inflammatory Bowel Disease in Children and Adolescents / Raymond S.B., Gee M.S., Anupindi S.A. [et al.] // J. Pediatr Gastroenterol. Nutr. — 2016. — ​Vol. 63, № 1. doi: 10.1097/MPG.0000000000001225.

Elevated pancreatic enzymes in inflammatory bowel disease are associated with extensive disease / Heikius B., Niemelä S., Lehtola J., Karttunen T.J. // Am. J. Gastroenterol. — 1999. — ​Apr. — 94(4). — ​P. 1062-9.

ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents / Levine A., Koletzko S., Turner D. [et al.] // J. Pediatr. Gastroenterol. Nutr. — 2014. — № 58(6). — ​P. 795-806. doi: 10.1097/MPG.0000000000000239.

Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the United Kingdom. UK IBD Working Group on behalf of the British Society of Paediatric Gastroenterology Hepato­logy and Nutrition (BSPGHAN) / K. Sandhu, J.M.E. Fell, R.M. Beattie [et al.] // J. Pediatr. Gastroenterol. Nutr. — 2010 Feb. — 50 ­Suppl. 1. — ​S1-13. doi: 10.1097/MPG.0b013e3181c92c53.

Inflammatory Bowel Disease and Pancreatitis: A Review / Ramos L.R., Sachar D.B., DiMaio C.J. [et al.] // J. Crohns. Colitis. — 2016. — ​Vol. 10, № 1. — ​Р. 95-104. doi: 10.1093/ecco-jcc/jjv153.

Intestinal complications and extraintestinal manifestations in children with inflammatory bowel diseases / A. Stawarski, B. Iwan´czak, E. Krzesiek [et al.] // Pol. Merkur. Lekarski. — 2006. — № 20. — ​Р. 22-5.

Levine J.S. Extraintestinal Manifestations of Inflammatory Bowel Disease / J.S. Levine, R. Burakoff // Gastroenterology & He­patolog. — 2011. — № 7(4). — ​Р. 235-241.

Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines / Dan Turner, Arie Levine, Johanna C. Escher [et al.] // JPGN. — 2012. — ​Vol. 55. — ​Р. 340-361.

Pancreatic disorders in inflammatory bowel disease / Filippo Antonini, Raffaele Pezzilli, Lucia Angelelli, Giampiero Macarri // World. J. Gastrointest. Pathophysiol. — 2016 Aug 15. — ​Vol. 7(3). — ​P. 276-282. doi:10.4291/wjgp.v7.i3.276.

Rosen M.J. Inflammatory Bowel Disease in Children and Adolescents / M.J. Rosen, A. Dhawan, S.A. Saeed // JAMA Pediatr. — 2015. — № 169(11). — ​Р. 1053-60. doi: 10.1001/jamapediatrics.2015.1982.