The Antioxidant System of the Respiratory Tract Antioxidant Effectors in Supraepithelial and Extracellular Space (Part 2)

O.Ye. Abaturov, O.P. Volosovets, O.Ye. Khudiakov


The literature review presents the current data about the main antioxidant enzyme — lactoperoxidase (LPO), which functions exclusively in the bronchial secretion. The characteristics of LPO, induction of its synthesis, catalytic cycle of LPO and myeloperoxidase were described. The mechanism of LPO action, functioning of dual oxidases of the respiratory tract epithelial cells, LPO and thiocyanite anion interaction were considered in detail. The participation of LPO and myeloperoxidase in the antibacterial and antifungal protection was shown. Authors pre­sent other antioxidant enzymes of bronchoalveolar lavage fluid.


antioxidant system; respiratory tract; antioxidant effectors


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Copyright (c) 2020 O.Ye. Abaturov, O.P. Volosovets, O.Ye. Khudiakov

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