DOI: https://doi.org/10.22141/2224-0551.2.61.2015.75056

Immunoregulating Potential of Omega 3 Fatty Acids: Usage for Frequent Infectious Diseases Prevention in Children

L.S. Ovcharenko, A.A. Vertegel, T.G. Andrienko, N.V. Zhykhareva, I.V. Samokhin, A.V. Kryazhev

Abstract


Last years more and more investigations aim to study immune modulating function of long-chain polyunsaturated fatty acids (LCPUFA) the usage of which in practice could prevent development of acute respiratory diseases and allergic states. Among majority of LCPUFA omega 3 fatty acids are of greater interest. The authors of this article review several stu­dies and represents own investigation of impact of dietary supplement with omega 3 fatty acids complex («Omegami Smart Kid») on acute respiratory diseases reduction in children with recurrent forms of acute respiratory infectious pathology. Immunotropic action of dietary supplement of «Omegami Smart Kid» in children was associated with enhanced functioning of congenital and adaptive immunity. Immunoregulating target was associated with limited pro-inflammatory inclination of immunity as a nitro blue tetrazolium reduction test improvement, decreased CD25 and serum content of tumor necrosis factor α while an absence of concurrent immune suppression of anti-microbial protective potential.

Keywords


infections; omega 3 acids; immunotropic action; immunoregulating target.

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