Clinical Case of a Rare Immunodeficiency — Idiopathic CD4+-lymphocytopenia in Pediatrician’s Practice

O.V. Urbas, M.M. Malkovych, A.B. Stefanyshyn, O.A. Holodnykh, O.V. Pastukh, I.B. Parandii, L.V. Lupuliak


The article presents data on the prevalence, molecular and genetic aspects and potential mechanisms of idiopathic CD4+-lymphocytopenia occurrence, as well as the criteria for diagnosis in children and variants of the clinical course of this pathology. This is a rare immunity disorder with heterogeneous clinical manifestations (from asymptomatic course to severe opportunistic infections and deaths) and immunological profile. Practical observation of a clinical case of CD4+-lymphocytopenia in a child — a boy between the ages of 4 and 10 months of life has been described.


T-lymphocytes; immunodeficiency; children


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