DOI: https://doi.org/10.22141/2224-0551.2.70.2016.73796

Prognostic Criteria of Metabolic Syndrome Development in Children

T.V. Sorokman, М.-О.V. Popeliuk, К.Yu. Ushakova

Abstract


Introduction. The conduction of large-scale studies of metabolic syndrome (MS) prevalence in children and adolescents is complicated by the lack of consensus of opinion about the use of certain diagnostic criteria in pediatric practice. Objective: to examine the features of family history in children with overweight and obesity and establish their diagnostic and prognostic value. Material and methods. The study included 158 children (100 children with overweight and 58 children with obesity) and 70 children with normal body weight (control group). The results of research were analyzed using computer package «Statistica» StatSoft Inc. and Excel XP for Windows on a personal computer. Results. 32.7 % of children in the main group were hereditary taint on one diagnostic criteria of the MS, 30.4 % had two diagnostic criteria and 24.1 % had all the three criteria of MS, and the more excess body weight a child was suffering from, the greater was hereditary taint on the number of metabolic syndrome criteria (p < 0.05). In the control group of children, hereditary tainted on cardiovascular disease risk factors were 17.2 % — for obesity, 18.9 % — for hypertension, 17.2 % — for ischemic heart disease and 6.8 % — for carbohydrate metabolism disorders. Conclusions. 1. In 32.7 % of cases children were hereditary tainted on one diagnostic criterion of metabolic syndrome, 30.4 % patients had two and 24.1% children had all the three criteria of MS. 2. Presence of a positive family history of the child significantly increases the risk of child’s obesity: PR = 10.59 (95% CI: 3.81–31.79) at ER = 1.68 (95 % CI: 1.43–1.82).


Keywords


children; metabolic syndrome; hereditary risk factors

References


Балыкова Л.А. Лечение метаболического синдрома у детей и подростков / Л.А. Балыкова, О.М. Солдатов, Е.С. Самошкина, А.А. Самошкина // Педиатрия. — 2011. — Т. 90, № 2. — С. 88-95.

Васюкова О.В. Инсулинорезистентность при ожирении у детей: спорность оценки / О.В. Васюкова, А.В. Витебская // Проблемы эндокринологии. — 2009. — Т. 55, № 3.

Полубояринова И.В. Антропометрические, метаболические и гормональные особенности течения ожирения, дебютировавшего в детском, подростковом и репродуктивном возрасте / И.В. Полубояринова // Международый эндокринологический журнал. — 2010. — № 3(27). — С. 22-27.

Протоколи надання медичної допомоги дітям за спеціальністю «Дитяча ендокринологія». Наказ № 254 від 27.04.2006.

Сенаторова Г.С. Метаболічні та гемодинамічні аспекти кардіоваскулярного ризику у підлітків з надлишковою вагою та ожирінням / Г.С. Сенаторова, Т.В. Чайченко // Перинатология и педиатрия. — 2012. — № 2. — С. 101-106.

Томашевська О.Я., Дзісь Є.І. Метаболічний синдром: підходи до діагностики, лікування та реабілітації / О.Я. Томашевська, Є.І. Дзісь // Журнал АМН України. — 2006. — Т. 12, № 2. — С. 282-295.

Аndrabi S.M.S. Prevalence of MS in 8–18 year old school-going children of Srinagar City of Kashmir India / S.M.S. Аndrabi, M.H. Bhat, S.R.S. Andrabi [et al.] // Ind. J. Endocrinol. Metab. — 2013. — 17(1). — 95-100.

Eiland L.S. Use of statins for dyslipidemia in the pediatric population / L.S. Eiland, P.K. Luttrell // JPPT. — 2010. — 15(3). — 160-172.

IDF Epidemiology Task Force Consensus GrouP. The metabolic syndrome a new worldwide definition / K.G. Alberti, P. Zimmet, J. Shaw [et al.] / Lancet. — 2005. — Vol. 366. — P. 1059-1062.

Reilly J.J. Obesity in childhood and adolescence: evidence based clinical and public health perspectives / J.J. Reilly // Postgrad. Med. J. — 2006. — 82(969). — 429-437.

Zimmet P. IDF Consensus. The metabolic syndrome in children and adolescents — an IDF consensus report [Text] / P. Zimmet, K.G. Alberti, F.T. Kaufman [et al.] // Pediat. Diabetes. — 2007. — 5. — 299-306.






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