DOI: https://doi.org/10.22141/2224-0551.15.4.2020.208473

Nutritional therapy in children with gastrointestinal disorders associated with the development of malabsorption syndrome

O.Yu. Belousova, L.V. Kazaryan

Abstract


Malabsorption syndrome, which means impaired intestinal digestion and absorption, is a “difficult” diagnosis in pediatric gastroenterology due to its polyetiological nature, polymorphism of clinical manifestations and obvious difficulties in verifying the diagnosis. Due to the wide range of possible disorders, the symptoms characterizing malabsorption can vary significantly; however, in most cases of the disease, the prevailing clinical symptom of the disease will be chronic diarrhea, and the most expected clinical consequence is deficient conditions typical for the development of malnutrition. The article provides data on modern classifications of diseases characterized by disorders of digestion and absorption, as well as clinical aspects that help with the differential diagnosis. The importance of careful collecting medical history data, examining a child, and conducting routine physical examination is emphasized. Considering the severity of the clinical consequences of malnutrition and the importance of timely relief of nutritional deficiency, the need for timely nutritional support is highlighted, which will help to level the slowdown in physical development and growth disorders, as well as effectively prevent the decline in the general condition of the child and the progression of the underlying pathology that caused malabsorption syndrome. The use of mixtures to prevent the formation of severe metabolic and immunological disorders in children solves a number of problems associated with various aspects of the pathophysiological process. The active use in clinical practice of such universal therapeutic forms, which, in addition to therapeutic effect, can restore the patient’s nutritional status, has significantly reduced the need for parenteral nutrition and decreased the drug load on the sick child’s body.

Keywords


malabsorption syndrome; nutritional disease; children; malnutrition; nutritional status

References


Montalto M, Santoro L, D'Onofrio F, et al. Classification of malabsorption syndromes. Dig Dis. 2008;26(2):104-111. doi:10.1159/000116767.

Tkach SM, Sizenko AK. Malabsorption syndrome: new classification, main causes and mechanisms of development. Modern gastroenterology. 2012;(65):114-121. (in Russian).

Ruiz AR Jr. Overview of malabsorption. Available from: https://www.msdmanuals.com/en-jp/professional/gastrointestinal-disorders/malabsorption-syndromes/overview-of-malabsorption. Accessed: October 2019.

Bordii TA. Malabsorption syndrome in children (part 3). Z turbotoyu pro ditinu. 2017;(3):10-14. (in Russian).

Johlin FC Jr, Panther M, Kraft N. Dietary fructose intolerance: diet modification can impact self-rated health and symptom control. Nutr Clin Care. 2004;7(3):92-97.

Belousova OYu. Rare forms of malassimilation syndrome in children. Zdorov’ja Ukrai'ny. Pediatrija. 2010;(15):54-55. (in Russian).

Guarino A, Branski D, Winter HS. Chronic diarrhea. In: Kliegman RM, Stanton BF, St Geme III JW, Schor NF, editors. Nelson Textbook of Pediatrics. 20th ed. Philadelphia: Elsevier; 2016. 1875-1887 pp.

Schmitz J. Maldigestion and malabsorption. In: Walker WA, Durie PR, Hamilton JR, et al., editors. Pediatric gastrointestinal disease: pathophysiology, diagnosis, management. 2nd ed. St Louis: Mosby; 2000. 51-58 pp.

Gupte S. Chronic diarrhea: four decades experience in resource-limited settings. Int J Gastroenterol Hepatol Transpl Nutr. 2016;(1):78-84.

Savilahti E. Food-induced malabsorption syndromes. J Pediatr Gastroenterol Nutr. 2000;30 Suppl:S61-S66. doi:10.1097/00005176-200001001-00010.

Sandoz AE. Chronic diarrhea in childhood: a therapeutic problem. Eur Physician. 2011;(4):23-29.

Gupte S, Gupte N, Anderson L, Anderson RA. Diarrheal diseases. In: Gupte S, Gupte SB, Gupte M, editors. Recent Advances in Pediatrics: Pediatric Gastroenterology, Hepatology and Nutrition (Special Vol 23). New Delhi: Jaypee; 2013. 57-81 pp. doi:10.5005/jp/books/11925.

Gupte S. Chronic diarrhea and malabsorption: Are they synonymous. Eur Chr Gastroenterol 2015;(4):126-128.

Belousova OYu. Diarrheal syndrome in children and adolescents: the features of pathogenetic therapy. Zdorov'e rebenka. 2018;13(Suppl 1):1-6. doi:10.22141/2224-0551.13.0.2018.131170. (in Russian).

Behera B, Mirdha BR, Makharia GK, Bhatnagar S, Dattagupta S, Samantaray JC. Parasites in patients with malabsorption syndrome: a clinical study in children and adults. Dig Dis Sci. 2008;53(3):672-679. doi:10.1007/s10620-007-9927-9.

Thomas PD, Forbes A, Green J, et al. Guidelines for the investigation of chronic diarrhoea, 2nd edition. Gut. 2003;52 Suppl 5(Suppl 5):v1-v15. doi:10.1136/gut.52.suppl_5.v1.

El Mouzan MI. Chronic diarrhea in children: part II. Clinical approach and management. Saudi J Gastroenterol. 1995;1(2):81-86.

Thornton-Wood C, Saduera Sh, Burke M, Silbernagl L, Kuter H. To evaluate the acceptability, gastrointestinal tolerance and compliance of a low-calorie peptide based paediatric tube feed formula. In: ЕSPGHAN Annual Meeting 2020: Congress Abstract. January 29-31, 2020; Brighton, UK. Brighton; 2020.

Leonard M, Caldari D, Mas E, et al. Experience of Using a Semielemental Formula for Home Enteral Nutrition in Children: A Multicenter Cross-sectional Study. J Pediatr Gastroenterol Nutr. 2019;68(4):585-590. doi:10.1097/MPG.0000000000002236.






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