DOI: https://doi.org/10.22141/2224-0551.15.1.2020.196754

Functional gastrointestinal disorders in infants: to treat, observe or correct?

O.Yu. Belousova, L.V. Kazaryan

Abstract


The article discusses the functional disorders of the gastrointestinal tract in infants. The prevalence of functional gastrointestinal disorders is extremely high in all age groups, but in young children, functional diseases are actually a normal variant: mostly, a medical practitioner has to deal with functional digestive disorders in young children, which leads to increased interest of pediatricians in their etiology, pathogenesis and therapy. The most common gastrointestinal disorders are infant colic, regurgitation and constipation — they make up the majority of complaints experienced by parents of children of the first year of life who turn to a pediatrician. Despite the fact that these disorders do not pose a great danger to life and, as a rule, do not significantly affect children’s health in future, they have a significant impact on the quality of life, lead to a large number of unjustified hospitalizations, using excessive pharmacotherapy, and violate the psychological climate in the family. Therefore, it is advisable to carry out the correction of functional gastrointestinal disorders not with the help of medicines, but by prescribing functional food products, in particular breast milk substitutes, which children who are on artificial feeding receive. Questions related to the use of formulas, which are breast milk substitutes, especially those that able to correct minor digestive dysfunctions, are a major trending topic for discussion by clinicians and pediatricians.


Keywords


functional gastrointestinal disorders; Rome criteria; regurgitation; infant colic; constipation; functional nutrition

References


Drossman DA, Hasler WL. Rome IV-Functional GI Disorders: Disorders of Gut-Brain Interaction. Gastroenterology. 2016;150(6):1257–1261. doi:10.1053/j.gastro.2016.03.035.

Benninga MA, Faure C, Hyman PE, St James Roberts I, Schechter NL, Nurko S. Childhood Functional Gastrointestinal Disorders: Neonate/Toddler. Gastroenterology. 2016;S0016-5085(16)00182-7. doi:10.1053/j.gastro.2016.02.016.

Zakharova IN, Sugyan NG, Berezhnaya IV. Functional gastrointestinal disorders in the infants: diagnostics criteria and approaches to the dietary therapy. Rossiyskiy Vestnik Perinatologii i Pediatrii. 2018;63:(1):113–121. doi: 10.21508/10274065-2018-63-1-113-121. (in Russian).

Iacono G, Merolla R, D'Amico D, et al. Gastrointestinal symptoms in infancy: a population-based prospective study. Dig Liver Dis. 2005;37(6):432–438. doi:10.1016/j.dld.2005.01.009.

Dubrovskaya MI, Gryaznova EI. Functional gastrointestinal disorders in infants which reflect the disorders in the relationships in mother-child dyad. Lechaschii Vrach. 2019;(6):19—23. doi:10.26295/OS.2019.54.11.004. (in Russian).

Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258–274. doi:10.1097/MPG.0000000000000266.

Vandenplas Y, Rudolph CD, Di Lorenzo C, et al. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN). J Pediatr Gastroenterol Nutr. 2009;49(4):498–547. doi:10.1097/MPG.0b013e3181b7f563.

Lebron D, Vasconcellos E. The Episodic Syndromes That Maybe Associated with Migraines. Semin Pediatr Neurol. 2016;23(1):6–10. doi:10.1016/j.spen.2016.01.003.

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1–211. doi:10.1177/0333102417738202.

Rhoads JM, Fatheree NY, Norori J, et al. Altered fecal microflora and increased fecal calprotectin in infants with colic. J Pediatr. 2009;155(6):823–828.e1. doi:10.1016/j.jpeds.2009.05.012.

Belousova OYu. The modern view on functional constipation in infants: features of feeding and principles of non-pharmacological correction. Zdorov'e rebenka. 2015;(60):140–153. doi:10.22141/2224-0551.14.0.2019.165514. (in Russian).

Vandenplas Y, Levy E, Lemmens R, Devreker T. Functional constipation in children. Pediatriia. Consilium Medicum. 2017;(1):50-57. doi:10.1016/j.jpedp.2018.05.008. (in Russian).

Lewis ML, Palsson OS, Whitehead WE, van Tilburg MAL. Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents. J Pediatr. 2016;177:39–43.e3. doi:10.1016/j.jpeds.2016.04.008.

Rouster AS, Karpinski AC, Silver D, Monagas J, Hyman PE. Functional Gastrointestinal Disorders Dominate Pediatric Gastroenterology Outpatient Practice. J Pediatr Gastroenterol Nutr. 2016;62(6):847–851. doi:10.1097/MPG.0000000000001023.

Van Tilburg MA, Hyman PE, Walker L, et al. Prevalence of functional gastrointestinal disorders in infants and toddlers. J Pediatr. 2015;166(3):684–689. doi:10.1016/j.jpeds.2014.11.039.

Nelson SP, Chen EH, Syniar GM, Christoffel KK. Prevalence of symptoms of gastroesophageal reflux during infancy. A pediatric practice-based survey. Pediatric Practice Research Group. Arch Pediatr Adolesc Med. 1997;151(6):569–572. doi:10.1001/archpedi.1997.02170430035007.

Dubrovskaya MI, Gryaznova EI. Functional gastrointestinal disorders in infants which reflect the disorders in the relationships in mother-child dyad. Lechaschii Vrach. 2019;(6):19—23. doi:10.26295/OS.2019.54.11.004. (in Russian).

Zeevenhooven J, Browne PD, L'Hoir MP, de Weerth C, Benninga MA. Infant colic: mechanisms and management. Nat Rev Gastroenterol Hepatol. 2018;15(8):479–496. doi:10.1038/s41575-018-0008-7.

Alexander CP, Zhu J, Paul IM, Kjerulff KH. Fathers make a difference: positive relationships with mother and baby in relation to infant colic. Child Care Health Dev. 2017;43(5):687–696. doi:10.1111/cch.12445.

Al Dhaheri W, Diksic D, Ben-Shoshan M. IgE-mediated cow milk allergy and infantile colic: diagnostic and management challenges. BMJ Case Rep. 2013;2013:bcr2012007182. doi:10.1136/bcr-2012-007182.

Drug and Therapeutics Bulletin Editorial Office. Management of infantile colic. BMJ 2013;347:f4102. doi:10.1136/bmj.f4102.

Wojtyniak K, Szajewska H. Systematic review: probiotics for functional constipation in children. Eur J Pediatr. 2017;176(9):1155–1162. doi:10.1007/s00431-017-2972-2.

James-Roberts IS, Alvarez M, Hovish K. Emergence of a developmental explanation for prolonged crying in 1- to 4-month-old infants: review of the evidence. J Pediatr Gastroenterol Nutr. 2013;57:S30–S36. doi:10.1097/01.mpg.0000441932.07469.1.

Kidd M, Hnatiuk M, Barber J, Woolgar MJ, Mackay MP. "Something is wrong with your milk": Qualitative study of maternal dietary restriction and beliefs about infant colic. Can Fam Physician. 2019;65(3):204–211.

Harb T, Matsuyama M, David M, Hill RJ. Infant Colic-What works: A Systematic Review of Interventions for Breast-fed Infants. J Pediatr Gastroenterol Nutr. 2016;62(5):668–686. doi:10.1097/MPG.0000000000001075.

Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258–274. doi:10.1097/MPG.0000000000000266.

Belousova OYu. Functional constipation in infants in the light of Rome IV criteria. International recommendations. Zdorov'e rebenka. 2019;14(Suppl 1):16–24. doi: 10.22141/2224-0551.14.0.2019.165514. (in Russian).

Skórka A, Pieścik-Lech M, Kołodziej M, Szajewska H. Infant formulae supplemented with prebiotics: Are they better than unsupplemented formulae? An updated systematic review. Br J Nutr. 2018;119(7):810–825. doi:10.1017/S0007114518000120.

Ben XM, Li J, Feng ZT, et al. Low level of galacto-oligosaccharide in infant formula stimulates growth of intestinal Bifidobacteria and Lactobacilli. World J Gastroenterol. 2008;14(42):6564–6568. doi:10.3748/wjg.14.6564.

Giovannini M, Verduci E, Gregori D, et al. Prebiotic effect of an infant formula supplemented with galacto-oligosaccharides: randomized multicenter trial. J Am Coll Nutr. 2014;33(5):385–393. doi:10.1080/07315724.2013.878232.

González-Bermúdez CA, López-Nicolás R, Peso-Echarri P, Frontela-Saseta C, Martínez-Graciá C. Effects of different thickening agents on infant gut microbiota. Food Funct. 2018;9(3):1768–1778. doi:10.1039/c7fo01992k.






Copyright (c) 2020 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2020

 

   Seo анализ сайта