DOI: https://doi.org/10.22141/2224-0551.14.6.2019.179241

Clinical and functional portrait of infants with regurgitation syndrome

S.I. Ilchenko, T.V. Mozheiko, N.M. Kramarenko, N.V. Duplenko

Abstract


Background. Regurgitation syndrome is widely spread among young children and can be a sign of both age anatomical and functional features and serious pathological conditions. Pre­sence of the syndrome requires a careful etiological clarification for choosing therapeutic management (only observation or correction) during out-patient treatment. The purpose of the study was to evaluate characteristics of infants with regurgitation syndrome based on anamnestic, clinical and functional data analysis. Materials and methods. Fifty-four infants aged from 1 month to 2 years with regurgitation syndrome and other manifestations of functional gastrointestinal disorders (FGID) participated in this investigation. The patients were divided into two clinical groups: I group involved the patients with isolated regurgitation syndrome; II group consisted of the patients with the association of syndrome manifestations and other FGID. General clinical studies were carried out for all the patients. Hydrogen breath test (HBT) with nutritional lactose load was performed in 32 children. Results. All infants with FGID presented with regurgitation syndrome: in I group 18.5 % cases, in 81.5 % cases in combination with other FGID, in 24.1 % cases — in anamnesis only. Peculiarities of the courses of isolated syndrome manifestations were as follows: the higher intensity of regurgitation, absence of general condition disorders in a child and in physical development, a high percentage of children born by caesarean section and whose mothers had toxicosis. Frequent disorder of children’s behaviour (anxiety, sleep disturbance) and feeding technique, shortening of the time for introducing the first feeding and free feeding schedule are typical for combined manifestations. Positive results for HBT were received in 18.8 % children, doubtful ones were received in 31.2 % children. Conclusions. The results of the investigations made it possible to find out some clinic functional features of regurgitation syndrome in infants. It can be useful for observing and choosing clinical approach in practice.


Keywords


regurgitation syndrome; functional gastrointestinal disorders; infants

References


Lezhenko GO, Pashkova OJe. Therapeutic possibilities for the correction of functional digestive disorders in young children. Zdorovʹe rebenka. 2018;13(5):57-60. (in Ukrainian).

Starostina LS, Yablokova EA. Features of the functioning of the digestive system in young children: correction of the most common disorders. RMJ. 2017;25(19):1335-1340. (in Russian).

Tkach RV, Nyankovskyy SL, Nyankovska OS, Yatsula MS. The incidence of functional disorders and clinical symptoms that may be associated with lactase deficiency in infants of Lviv. Zdorovʹe rebenka. 2016;(73.1):60-64. doi: 10.22141/2224-0551.5.1.73.1.2016.78942. (in Ukrainian).

Shadrin OG, Marushko TL, Polkovnychenko LM. Modern approaches to the treatment of regurgitation syndrome in young children. Zdorovʹe rebenka. 2012;(41):73-78. (in Ukrainian).

Rybkina NL. Functional disoders of the digestive system in children under one year: clinical manifestations, modern approaches to correction. Vestnik Sovremennoi Klinicheskoi Mediciny. 2016;9(2):70-76. doi: 10.20969/VSKM.2016.9(2).70-76. (in Russian).

Hyman PE, Milla PJ, Benninga MA, Davidson GP, Fleisher DF, Taminiau J. Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology. 2006 Apr;130(5):1519-26. doi: 10.1053/j.gastro.2005.11.065.

Marushko YuV, Iovitsa TV. Use of hydrogen respiratory dough for determination of tranzitornaya laktase deficiency for children of the first half-year of life. Perynatologiya i pediatriya. 2013;(56):81-84. doi: 10.15574/PP.2013.56.51. (in Russian).

Ilchenko SI, Nedielska SM, Mozheiko TV. The peculiarities of using and reading of hydrogen breath test results with lactose load in young children and their mothers. Patologia. 2019;16(45):116-123. doi: 10.14739/2310-1237. 2019.1.16647. (in Ukrainian).

Marushko YuV, Zelena NA, Melnikov OF, Movchan OS. State of local immunity in children with frequent respiratory infections. Aktualʹnaâ Infektologiâ. 2013;(1):65-67. doi: 10.22141/2312-413x.1.01.2013.82609. (in Ukrainian).

Abaturov OYe, Volosovets OP, Khudiakov OYe. The antioxidant system of the respiratory tract antioxidant effectors in supraepithelial and extracellular space (part 2). 2016;(72):92-99. doi: 10.22141/2224-0551.4.72.2016.76597. (in Russian).

European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN). ESPGHAN Guidelines. Available from: http://www.espghan.org/guidelines/.

Shadrin OG, Nyankovskyy SL, Beketova GV, et al. Osoblyvosti diagnostyky ta pidhody do likuval'no-profilaktychnogo harchuvannja ditej rann'ogo viku z funkcional'nymy rozladamy travnoi' systemy: metodychni rekomendacii' [Diagnostic features and approaches to therapeutic and prophylactic nutrition of young children with functional disorders of the digestive system: guidelines]. Kyiv: Liudy v bilomu; 2016. 28 p. (in Ukrainian).

Korenjuk OS. The effectiveness of clinical nutrition in the treatment of regurgitation syndrome in infants. Medychnyj forum. 2014;(2):93-99. (in Ukrainian).

Zakharova IN, Sugian NG, Andriukhina EN, Dmitrieva IuA. Pediatrician tactics for infant intestinal colic. RMJ. 2010;18(1):11-15. (in Russian).

Stepanov OG, Zhakov IaI, Teplova SN. Clinical features of an irritated intestinal syndrome in children. Human. Sport. Medicine. 2005;(44):288-291. (in Russian).

Babaian ML. Modern approaches to the correction of regurgitation in young children. Perspektivy meditsiny. Praktika pediatra. 2013;(2):116-119. (in Russian).






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