The effectiveness of ozone therapy as a non-drug method for treatment of initial caries of permanent teeth in children

R.P. Oliynyk, M.M. Rozhko, V.S. Habchuk


Background. It is proved that the use of ozone will contribute to the growth of caries dental resistance, but the question about the adequacy of this method for the complete restoration of the already partly demineralized enamel structure remains controversial. Therefore, the purpose of our study was to determine the effectiveness of the isolated use of ozone for the treatment of initial caries of permanent teeth in children of different age groups (6, 12 and 15 years old). Materials and me­thods. We have performed treatment of initial caries with Ozone DTA/Ozonymed in 60 patients aged 6 to 15 years. CRT test was used to assess the structural resistance of enamel to the action of the acid factor. The enamel resistance to caries was determined using a modified enamel resistance of teeth test. The statistical processing of the study results was carried out in the Microsoft Excel 2017 software using arithmetic mean, arithmetic mean deviations, Pearson, Spearman and point-biserial correlation coefficients. Results. Results of the initial topographical distribution of caries lesions analysis showed a statistically higher (p ≤ 0.05) frequency of chewing teeth fissure defeat (36.67 %) compared with pathology of another localization. The sites of initial caries in 58.33 % of the examined persons were found on the upper jaw, in 46.67 % — on the lower. There was a decrease in the number of patients with a maximum and high risk of caries progression within a month of treatment — by 3.33 and 5.0 %, respectively. And three months later, the reduction in the number of patients with high risk of caries progression was documented (by 49.98 %). The finding indicate a positive ozone effect in terms of enamel resistance index increasing. However, none of the patients ma­naged to achieve a complete reduction of carious spot, although a significant percentage of examined children noted a decrease in its size to those that statistically differed from the initial ones (p < 0.05). Conclusions. Feasibility of non-drug methods of initial caries treatment implementation was justified, however, the effectiveness of isolated ozone use is not enough.


children; caries; enamel resistance of teeth; remine­ralizing therapy; ozone therapy; Ozone DTA device


Antonenko M, Zelinskaya N, Znachkova O, Shuminskaya T, Pariy A, Syroyishko M. Foundation tactics of treatment enamel caries in adolescents, genetically determined to carious disease. Sovremennaya stomatologiya. 2016;(81):16-19. (in Ukrainian).

World Health Organisation (WHO). Oral health. Available from: Accessed: September 24, 2018.

Melnychuk HM, Lychkovska OL. Alternative non-drug methods of the antimicrobial treatment of parodontium diseases: ozone therapy and photodynamic therapy; the mechanism of action, indication and contraindication to using. Clinical Dentistry. 2015;(1):28-37. (in Ukrainian).

Potapchuk AM, Dobra PP, Rusyn VV, Rivis OYu. Suchasna fizioterapija ta diagnostyka v stomatologii' [Modern physiotherapy and diagnostics in dentistry]. Uzhhorod: Breza AE; 2012. 450 p. (in Ukrainian).

World Health Organisation (WHO). Resolution WHA60.17. Oral health: action plan for promotion and integrated disease prevention. Available from: Accessed: May 23, 2007.

Chekman IS, Bobyrov VM, Kresjun VJ, et al., authors; Chekman IS, editor. Farmokologija: pidruchnyk dlja studentiv [Pharmacology: a student book]. Vinnytsia: Nova Knyga; 2014. 432 p. (in Ukrainian).

German IJS, Rodrigues AC, Andreo JC, et al. Ozone therapy in dentistry: A systematic review. Int J Odontostomat. 2013;7(2): 267-278.

Huth KC, Paschos E, Brand K, Hickel R. Effect of ozone on non-cavitated fissure carious lesions in permanent molars. A controlled prospective clinical study. Am J Dent. 2005 Aug;18(4):223-8.

Saini R. Ozone therapy in dentistry: A strategic review. J Nat Sci Biol Med. 2011 Jul;2(2):151-3. doi: 10.4103/0976-9668.92318.

Naik SV, Rajeshwari K, Kohli S, Zohabhasan S, Bhatia S. Ozone - A Biological Therapy in Dentistry - Reality or Myth????? Open Dent J. 2016 May 11;10:196-206. doi: 10.2174/1874210601610010196.

Zaura E, Buijs MJ, ten Cate JM. Effects of ozone and sodium hypochlorite on caries-like lesions in dentin. Caries Res. 2007;41(6):489-92. doi: 10.1159/000109086.

Copyright (c) 2019 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2020


   Seo анализ сайта