The risk prediction of acute simple bronchitis’ prolonged duration in children


  • O.O. Ahafonova State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine
  • N.M. Tokarieva State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, Ukraine



acute simple bronchitis, children, forecasting of prolonged duration, risk factors


Background. Factors and mechanisms for the formation of a long course of acute simple bronchitis in children today are unknown finally. The participation of a big number different factors, including clinical, laboratory immunological indicators, is described. The purpose of the study: identifying informatively significant clinical-anamnestic, laboratory and immunological risk factors for the long-term course of bronchitis in young children, as well as the creation of a mathematical model for predicting the likelihood of developing this situation. Materials and methods. We’ve examined 122 children aged from 1 to 6 years old with acute simple bronchitis who were at the examination and treatment in the infectious department of the Dnipropetrovsk municipal clinical hospital №1. Results. Risk factors were determined and a mathematical model for predicting the development of long-term course of acute simple bronchitis in children was created. Prognostic significance has been obtained: the body weight of the baby at birth is more than 3.7 kg, mother's smoking, background conditions such as perinatal CNS and chronic tonsillitis, low-grade body temperature, duration of fever over 4.7 days, and levels of g-interferon and a-defensins in the oropharyngeal fluid. Conclusions. The obtained results have shown that the development of the long course of acute simple bronchitis in children is influenced by clinical-anamnestic, laboratory and immunological factors. The given mathematical model of forecast can be used in the practical activity of family physicians and pediatricians.


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Clinical Pediatrics