DOI: https://doi.org/10.22141/2224-0551.14.2.2019.165821

Quorum sensing inhibitors of bacteria Streptococcus pneumoniae

А.Е. Abaturov, Т.А. Kryuchko

Abstract


The scientific review systematizes information on LuxS/AI-2 and ComABCDE quorum sensing systems of bacteria Streptococcus pneumoniae. It is emphasized that biofilms of bacteria Streptococcus pneumoniae are one of the mechanisms of antibiotic resistance and a source of highly invasive bacterial clones. A brief description of 5-azacytidine, sinefungin and pyrimidinedione, which have a specific anti-biofilm effect, is given.

Keywords


quorum sensing; Streptococcus pneumoniae; quorum sensing inhibitors

References


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