DOI: https://doi.org/10.22141/2224-0551.14.2.2019.165821
Quorum sensing inhibitors of bacteria Streptococcus pneumoniae
Abstract
The scientific review systematizes information on LuxS/AI-2 and ComABCDE quorum sensing systems of bacteria Streptococcus pneumoniae. It is emphasized that biofilms of bacteria Streptococcus pneumoniae are one of the mechanisms of antibiotic resistance and a source of highly invasive bacterial clones. A brief description of 5-azacytidine, sinefungin and pyrimidinedione, which have a specific anti-biofilm effect, is given.
Keywords
quorum sensing; Streptococcus pneumoniae; quorum sensing inhibitors
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Abaturov AE, Bolbot YuK, Alifanova SV, et al. [Pneumococcal infection in children (monograph)]. Khmelnitsky: FLPstorozhuk; 2016. 200 p. (in Russian).
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