Systemic circulation in children with diet-related diseases

Yu.N. Nechytailo, T.N. Mikhiеieva, O.Ya. Pidmurniak, N.I. Kovtyuk


Background. The basic group of diet-related diseases is gastroenterological pathology, obesity, metabolic syndrome and diabetes mellitus. One of the leading mechanisms in the course of these pathologies is an imbalance in the autonomic system, which is accompanied by disorders of the systemic circulation, including blood pressure regulation. The purpose of the study was to analyze the characteristics of nutrition and to assess the blood pressure in children with diet-related diseases. Materials and methods. One-hundred and two school-age children who were hospitalized in various departments for chronic gastroduodenitis (the first group — 90 children) and endocrine pathology — the hypothalamic obesity syndrome (the second group — 21 children) and diabetes (the third group — 31 children) were examined. Features of the regime and quality of food were studied on a specially designed questionnaire. The status of systemic circulation was determined using an office measurement of blood pressure and daily blood pressure monito­ring. The results of the children examination were processed ­using Statistics 6.0. Results. Analysis of the nutrition of children has revealed a significant imbalance and a significant difference in a frequency of food consumption among schoolchildren. Having evaluated the level of blood pressure in children according to the reciprocal tables, a significantly larger number of detected pre-hypertension and hypertension cases in individuals in the 2nd and 3rd groups are observed compared with the 1st group. These children have variability in daily blood pressure monitoring, which may be associated with an imbalance of the autonomic nervous system. Conclusions. Imbalanced nutrition contributes to the development of such diet-related diseases. Changes in the systemic circulation in the examined children are associated with the peculiarities of the autonomic regulation of the endocrine and digestive systems, which indicates the combined pathogenetic mechanisms of the development of the pathology of both systems.


children; arterial hypertension; chronic gastroduodenitis; diabetes mellitus; obesity


Beketova GV. Chronic gastroduodenitis in children and adolescents: epidemiology, etiology, pathogenesis, diagnosis (part I). Dytiachyi likar. 2012;(19):20-24. (in Ukrainian).

Malfertheiner P, Megraud F, O'Morain CA, et al. Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut. 2012 May;61(5):646-64. doi: 10.1136/gutjnl-2012-302084.

Bobrova VI, Koshova AO, Vorobienko YuI. Age features of the clinical course of chronic gastroduodenal pathology in children. Perinatologiya i pediatriya. 2013;(54):73-77. (in Russsian).

Majdannyk VG, Hajtovych MV. Primary arterial hypertension in adolescents: problematic issues and prospects. Pediatrija, akusherstvo ta ginekologija. 2012;(4):90-91. (in Ukrainian).

Agapitov LI, Bereznitskaia VV, Bolbikov VV, et al., authors; Belozerov IuM, editor. Clinical Cardiology. Vol 5. In: Tsaregorodtsev AD, Tabolin VA, editors. Rukovodstvo po farmakoterapii zabolevanii detskogo vozrasta [Guidelines for the pharmacotherapy of childhood diseases]. Moscow: Medpraktika-M; 2004. 177-201 pp. (in Russian).

Іvanov DD, Ivanova TD. Hypertension in children. Cardiorenal syndrome. Sovremennaya pediatriya. 2011;(36):160-162. (in Russian).

Liang Y, Mi J. Pubertal hypertension is a strong predictor for the risk of adult hypertension. Biomed Environ Sci. 2011 Oct;24(5):459-66. doi: 10.3967/0895-3988.2011.05.002.

Saha I, Paul B, Mukherjee A, Biswas R, Dasgupta A. Validity of the WHO criteria for adolescent hypertension. East Afr J Public Health. 2011 Jun;8(2):135-7.

Chiolero A. The quest for blood pressure reference values in children. J Hypertens. 2014 Mar;32(3):477-9. doi: 10.1097/HJH.0000000000000109.

Davis CL. Undetected hypertension and prehypertension in children with diabetes need attention. J Pediatr. 2010 Aug;157(2):182-4. doi: 10.1016/j.jpeds.2010.04.022.

Maydannyk VG, Haytovych NV, Pavlyshyn GA, Ivanko AG, Nechytaylo YuN, Ocheretko VV. Prevalence of overweight and high blood pressure among schoolchildren in different regions of Ukraine. International Journal of Pediatrics, Obstetrics and Gynecology. 2013;3(1):33-39. (in Ukrainian).

Trushkina ІV, Leontyeva ІV. The cardiovascular system in children with obesity and arterial hypertension. Rossiyskiy Vestnik Perinatologii i Pediatrii. 2011;56(6):47-56. (in Russian).

Kharchenko N, Anokhina G. Obesity: Why is a lung at first sight so difficult to treat? Medicx Anti-Aging. 2011;(1):6-8. (in Russian).

Bancalari R, Díaz C, Martínez-Aguayo A, et al. Prevalence of hypertension in school age children and its association with obesity. Rev Med Chil. 2011 Jul;139(7):872-9. doi: /S0034-98872011000700007. (in Spanish).

Tsymbalista OL, Bobrykovych OS. Risk factors of metabolic syndrome manifestations development in older school age children. 2011;1:104-107. Sovremennaya pediatriya. 2011;(36):160-162. (in Russian).

Kovacs VA, Gabor A, Fajcsak Z, Martos E. Role of waist circumference in predicting the risk of high blood pressure in children. Int J Pediatr Obes. 2010 Apr;5(2):143-50. doi: 10.3109/17477160903111771.

Luma GB, Spiotta RT. Hypertension in children and adolescents. Am Fam Physician. 2006 May 1;73(9):1558-68.

Budreiko OA, Chumak SO, Nikitina LD. Formation of vascular disorders and microcir? Culation disturbances in childern and adolesсents with obesity. Perinatologiya i pediatriya. 2012;(50):107-109. (in Russian).

Savvo ID. Risk factors in the formation of dyslipidemia in adolescents with hypertension and obesity. Ukrainian Journal of Pediatric Endocrinology. 2014;2:90-91. (in Ukrainian).

Marushko JuV, Gyshhak TV. Daily monitoring of blood pressure is a modern method of controlling hypertension in children. Dytiachyi likar. 2011;(12):5-7. (in Ukrainian).

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