DOI: https://doi.org/10.22141/2224-0551.14.0.2019.165528

Gastric motility disorders in adolescents with gastroesophageal reflux disease and functional dyspepsia

V.L. Kashina-Yarmak, L.V. Kamarchuk, T.M. Kvaratskheliya

Abstract


Background. Gastric motility disorders in patients with upper gastrointestinal pathology are one of the key factors in the development of diseases as they disturb the well-being of patients and, therefore, require timely diagnosis and correction. The purpose was to establish the features of gastric motility in adolescents with functional dyspepsia and gastroesophageal reflux disease. Materials and methods. A total of 54 adolescents aged 12–18 years were examined, they were diagnosed with gastroesophageal reflux disease (70.4 %) and functional dyspepsia (29.6 %). Gastric emptying was studied by ultrasound examination of the upper gastrointestinal tract. Results. Functional dyspepsia and gastroesophageal reflux disease in adolescents develop against the background of gastric motility disorders, more often in the form of delayed gastric emptying, regardless of the form of the pathological process and the age of patients. In some patients, these disorders are chronic. Acceleration of gastric emptying is noted much less frequently, it is more typical for younger patients infected with Helicobacter pylori. Conclusions. General pathogenetic mechanisms underlie gastric motility disorders in functional dyspepsia and gastroesophageal reflux disease in adolescents. Evaluation and correction of gastric motility disorders are mandatory when monitoring patients with gastroduodenal pathology.


Keywords


functional dyspepsia; gastroesophageal reflux disease; adolescents; gastric motility

References


Drossman DA, Hasler WL. Rome IV-Functional GI Disorders: Disorders of Gut-Brain Interaction. Gastroenterology. 2016 May;150(6):1257-61. doi: 10.1053/j.gastro.2016.03.035.

Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016 Feb 19. pii: S0016-5085(16)00223-7. doi: 10.1053/j.gastro.2016.02.032.

Leushina EA, Chicherina EA. The modern idea of motor-evacuation violations of the upper section of the gastrointestinal tract (Review of literature). Lechaschii Vrach. 2015;(8):31. (in Russian).

Bel'mer SV, Havkin AI, Pechkurov DV. Funktsional'nye narusheniia organov pishchevareniia u detei. Printsipy diagnostiki i lecheniia v svete Rimskikh kriteriev IV [Functional disorders of the digestive system in children. Principles of diagnosis and treatment in the light of the Rome IV criteria]. Moscow : GEOTAR-Media; 2018. 160 p. (in Russian).

Zakharova IN, Osmanov IM, Pykov MI, et al. Instrumental diagnosis of functional disorders of the gastrointestinal tract in the practice of a pediatrician and a children's gastroenterologist. Pediatriia. Consilium Medicum. 2018;(1):79-89. doi: 10.26442/2413-8460_2018.1.79-89. (in Russian).

Till H, Thomson M, Foker JE, Holcomb GW, Khan KhM. Esophageal and Gastric Disorders in Infancy and Childhood. Berlin: Springer-Verlag; 2017. 1526 p. doi: 10.1007/978-3-642-11202-7.

Yulish EI, Chernysheva OE, Krivuschev BI, Glinskaya EV, Levchenko AA. Impairments of motor-evacuation activity of the digestive tract in children and its correction. Sovremennaya pediatriya. 2013;(50):17-19. (in Russian).

Hunt RH, Camilleri M, Crowe SE, et al. The stomach in health and disease. Gut. 2015 Oct;64(10):1650-68. doi: 10.1136/gutjnl-2014-307595.

Kugler TE. Prospects for using the new technique of ultrasound examination of the stomach with drinking load in the diagnosis of functional dyspepsia. Novosti Meditsiny i Farmatsii. Gastrojenterologiia. 2013;(478):65-68. (in Russian).

Dorofeev AE, Kugler TE, Silakov AI. Research regarding to pathophysiological mechnisms of functional dyspepsia using novel drinking ultrasonography test. Pytannja eksperymental'noi' ta klinichnoi' medycyny. 2013;17(2):14-21. (in Russian).

Sapozhnikov VG. Echography of the stomach and duodenum in children. Vestnik novyh medicinskih tehnologij. 2012;(1):62. (in Russian).

Terent'eva NG. Motorno-evakuatornaia funktsiia zheludka u zdorovykh i bol'nykh khronicheskimi gastritami detei v razlichnye vozrastnye periody. Diss. kand. med. Nauk [Motor-evacuation function of the stomach in healthy and sick children with chronic gastritis in different age periods. PhD diss.]. Chelyabinsk; 2004. 20 p. (in Russian).

Akopyan AN, Belmer SV, Vykhristyuk OF, Ardatskaya MD, Tshigoleva NE, Kalintseva VA. Gastroesophageal reflux and gastrointestinal-motility disorders. Doctor.Ru. 2014;(99):45-49. (in Russian).

Miwa H, Kusano M, Arisawa N, et al. Evidence-based clinical practice guidelines for functional dyspepsia. J Gastroenterol. 2015 Feb;50(2):125-39. doi: 10.1007/s00535-014-1022-3.

Kiranchuk NV. Gastric motility disorders in children with co-exiting pathology of esophagus and organs of gastroduodenal area. Sovremennaya pediatriya. 2019;(97):30-33. doi: 10.15574/SP.2019.97.30. (in Russian).

Makarova EG, Ukraintsev SE. Functional gastrointestinal disorders in infants: long-tern consequences and modern approaches for prevention and treatment. Pediatricheskaya Farmakologiya. 2017;14(5):392-399. doi: 10.15690/pf.v14i5.1788. (in Russian).

Katz РО, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013 Mar;108(3):308-28; quiz 329. doi: 10.1038/ajg.2012.444.

Tomkіv ZV, Korzhynskyi YS. Modern view of Helicobacter pylory infection (bibliografhical review). Buk Med Herald. 2011;(59):118-123. (in Ukrainian).

Khavkin AI, Komarova ON. Clinical and pathogenetic variants of antroduodenal motility disorders in children and their medicinal correction. Rossiyskiy Vestnik Perinatologii i Pediatrii. 2015;60(4):119-124. (in Russian).

Fedіv OI. Overlap syndrome in the functional gastroenterology. Zdorov’ja Ukrai'ny. Gastroenterologija, Gepatologija, Koloproktologija. 2019;(51):23-24. (in Ukrainian).

Quigley ЕММ, Lacy BE. Overlap of functional dyspepsia and GERD-diagnostic and treatment implications. Nat Rev Gastroenterol Hepatol. 2013 Mar;10(3):175-86. doi: 10.1038/nrgastro.2012.253.

Friesen CA, Rosen JM, Schurman JV. Prevalence of overlap syndromes and symptoms in pediatric functional dyspepsia. BMC Gastroenterol. 2016 Jul 25;16(1):75. doi: 10.1186/s12876-016-0495-3.

De Bortoli N, Natali V, Melissari S, Simonetti N, Tapete G, Marchi S. Overlap of GERD and gastrointestinal functional disorders. Minerva Gastroenterol Dietol. 2017 Sep;63(3):205-220. doi: 10.23736/S1121-421X.17.02398-4.




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