DOI: https://doi.org/10.22141/2224-0551.14.1.2019.157872

Analysis of doctors’ awareness of the fever correction principles in children

Yu.V. Marushko, T.V. Hyshchak

Abstract


Background. Fever in children is one of the most common causes for parents to see a doctor. The purpose was to analyze the state of awareness of doctors about the fever treatment principles in children, the methods of optimal dosage of antipyretic drugs and features of the antipyretic therapy use in certain categories of patients by means of specially designed questionnaires. Materials and methods. One hundred eight doctors took part in the survey. The questionnaire consisted of 20 questions. Results. Doctors note that only 66.0 % of parents use the means recommended by the doctor to reduce the body temperature in their children, the rest rely on personal experience and recommendations of pharmacists. 64.2 % of respondents indicated ibuprofen as a first-line antipyretic drug. 90.6 % of doctors believed an increase in body temperature to 38.5 °C or more to be an indication for the use of antipyretic drugs. However, 26.4 % of doctors use this group of drugs after vaccination; 17.0 % of respondents admit the use of antipyretic drugs at a child’s body temperature less than 38.5 °C, especially with a history of febrile convulsions, as well as pain syndrome and poor health. 50.9 % of respondents combine the use of ace­taminophen and ibuprofen if one of them is ineffective, using the second drug in the intervals between taking the first one. The most difficult questions for doctors were the peculiarities of the use of antipyretic drugs in children with comorbidities. Conclusions. Given the findings of the survey, we consider it necessary to conduct further work among physicians on awareness of the principles and indications for the use of antipyretic therapy in children.


Keywords


ibuprofen; acetaminophen; children; survey

References


Pigazzani F, Mackenzie I, MаcDonald TM. Ibuprofen and Paracetamol: Acceptably Safe for All? Drug Saf. 2018;41(11):999-1001. doi: 10.1007/s40264-018-0717-4.

Matok I, Elizur A, Perlman A, Ganor S, Levine H, Kozer E. Association of Acetaminophen and Ibuprofen Use With Wheezing in Children With Acute Febrile Illness. Ann Pharmacother. 2017;51(3):239-244. doi: 10.1177/1060028016678006.

Marushko YuV. Prevention and therapy of frequent and recurrent respiratory diseases in children is a topical issue of pediatrics. Sovremennaya pediatriya. 2006;2:32-36.

Fields E, Chard J, Murphy MS, Richardson M; Guideline Development Group and Technical Team. Assessment and initial management of feverish illness in children younger than 5 years: summary of updated NICE guidance. BMJ. 2013 May 22;346:f2866. doi: 10.1136/bmj.f2866.

de Bont EG, Francis NA, Dinant GJ, Cals JW. Parents' knowledge, attitudes, and practice in childhood fever: an internet-based survey. Br J Gen Pract. 2014 Jan;64(618):e10-6. doi: 10.3399/bjgp14X676401.

Bertille N, Fournier-Charriere E, Pons G, Chalumeau M. Managing fever in children: a national survey of parents' knowledge and practices in France. PLoS One. 2013 Dec 31;8(12):e83469. doi: 10.1371/journal.pone.0083469.

Luo S, Ran M, Luo Q, et al. Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial. Paediatr Drugs. 2017 Oct;19(5):479-486. doi: 10.1007/s40272-017-0237-1.

Community Paediatrics Committee. Fever Temperature Taking. Available from: https://www.caringforkids.cps.ca/handouts/fever_and_temperature_taking.

American Academy of Pediatrics Healthy Children. Fever (2012). Available from: https://www.healthychildren.org/English/health-issues/conditions/fever/Pages/default.aspx. Accessed: January 31, 2013.

Bridgwater K, Fletcher, M, Hatter, HE, Houghton, J, Mason, C, Monaghan J. Caring for children with fever. 2nd ed. London: Royal Collage of Nursing; 2013.

Section on Clinical Pharmacology and Therapeutics; Committee on Drugs, Sullivan JE, Farrar HC. Fever and Antipyretic Use in Children. Pediatrics. 2011 Mar;127(3):580-7. doi: 10.1542/peds.2010-3852.

NICE Guidance. Fever in under 5s: assessment and initial management. Available from: https://www.nice.org.uk/guidance/cg160. Accessed: 22 May 2013.

Green R, Jeena P, Kotze S, Lewis H, Webb D, Wells M. Management of acute fever in children: Guideline for community healthcare providers and pharmacists. S Afr Med J. 2013 Sep 3;103(12):948-54. doi: 10.7196/samj.7207.

Playne R, Anderson BJ, Frampton C, Stanescu I, Atkinson HC. Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial. Paediatr Anaesth. 2018 Dec;28(12):1087-1095. doi: 10.1111/pan.13517.

Chung AM. An evaluation of community pharmacy recommendations regarding alternating antipyretics in children. J Am Pharm Assoc (2003). 2018 Jul 21. pii: S1544-3191(18)30320-0. doi: 10.1016/j.japh.2018.06.015.

Chiappini E, Principi N, Longhi R, et al. Management of fever in children: summary of the Italian Pediatric Society guidelines. Clin Ther. 2009 Aug;31(8):1826-43. doi: 10.1016/j.clinthera.2009.08.006.

Bertille N, Purssell E, Hjelm N, et al. Symptomatic Management of Febrile Illnesses in Children: A Systematic Review and Meta-Analysis of Parents' Knowledge and Behaviors and Their Evolution Over Time. Front Pediatr. 2018 Oct 5;6:279. doi: 10.3389/fped.2018.00279.

Bertille N, Purssell E, Corrard F, Chiappini E, Chalumeau M. Fever phobia 35 years later: did we fail? Acta Paediatr. 2016 Jan;105(1):9-10. doi: 10.1111/apa.13221.

Marushko YuV, Boyko NS. Experience of using Nurofen® for children in pediatric practice. Ukrainian medical journal. 2014;2(100):83-85.

Marushko YuV. Nurofen® for children: questions and answers. Kyiv: Interservis; 2017. 78 p.

Beasley RW, Clayton TO, Crane J, et al. Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: International Study of Asthma and Allergies in Childhood Phase Three. Am J Respir Crit Care Med. 2011 Jan 15;183(2):171-8. doi: 10.1164/rccm.201005-0757OC.

Wickens K, Beasley R, Town I, et al. The effects of early and late paracetamol exposure on asthma and atopy: a birth cohort. Clin Exp Allergy. 2011 Mar;41(3):399-406. doi: 10.1111/j.1365-2222.2010.03610.x.

McBride JT. The association of acetaminophen and asthma prevalence and severity. Pediatrics. 2011 Dec;128(6):1181-5. doi: 10.1542/peds.2011-1106.

Sheehan WJ, Mauger DT, Paul IM, et al. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18;375(7):619-30. doi: 10.1056/NEJMoa1515990.

Sordillo JE, Scirica CV, Rifas-Shiman SL, et al. Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. J Allergy Clin Immunol. 2015 Feb;135(2):441-8. doi: 10.1016/j.jaci.2014.07.065.

Walsh P, Rothenberg SJ. Wheezing after the use of acetaminophen and or ibuprofen for first episode of bronchiolitis or respiratory tract infection. PLoS One. 2018 Sep 13;13(9):e0203770. doi: 10.1371/journal.pone.0203770.

Gulmez SE, Unal US, Lassalle R, Chartier A, Grolleau A, Moore N. Risk of hospital admission for liver injury in users of NSAIDs and nonoverdose paracetamol: Preliminary results from the EPIHAM study. Pharmacoepidemiol Drug Saf. 2018 Nov;27(11):1174-1181. doi: 10.1002/pds.4640.

Kanabar DJ. A clinical and safety review of paracetamol and ibuprofen in children. Inflammopharmacology. 2017 Feb;25(1):1-9. doi: 10.1007/s10787-016-0302-3.

Marushko YuV, Todyka YuІ, Garbar II. The evidence base of the effectiveness and safety of ibuprofen in pediatrics. Ukrainian medical journal. 2013;(97):77-80.




Copyright (c) 2019 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2019

 

   Seo анализ сайта