Functional disorders of the digestive tract in children: some aspects of correction

E.L. Krivusha, L.L. Petrenko


The article presents the main pathogenetic features of the development of functional disorders of the digestive tract in young children, as well as diagnostic criteria. A general description of Lactobacillus rhamnosus GG, the most studied probiotic strain in the world, is given, and the evidence of proven positive effects of bacteria on the macroorganism are presented. Pharmaceutical features of Active Flora baby, a new probiotic on the Ukrainian market, are described.


functional disorders; digestive tract; children; probiotic; Lactobacillus rhamnosus GG


Belyaeva IA, Yatsyk GV, Borovik TE, Skvortsova VA. Comprehensive approaches to the treatment and rehabilitation of children with gastrointestinal tract dysfunction. Voprosy Sovremennoi Pediatrii. 2006;5(3):109-113. (in Russian).

Belmer SV, Pechkurov DV. Roman consensus IV: a modern view on functional gastrointestinal disorders. Pediatric Nutrition. 2016;14(5):42-49. (in Russian).

Pechkurov DV, Gorelov AV. Dyspepsia syndrome in children: differential diagnosis, differential treatment approach. RMJ. 2012;20(24):1228-1232. (in Russian).

Frol'kis AV. Funktsional'nye zabolevaniia zheludochno-kishechnogo trakta [Functional diseases of the gastrointestinal tract]. Saint Petersburg: Meditsina; 1991. 224 p. (in Russian).

Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016 Feb 19. pii: S0016-5085(16)00223-7. doi: 10.1053/j.gastro.2016.02.032.

Paradise JL. Maternal and other factors in the etiology of infantile colic. Report of a prospective study of 146 infants. JAMA. 1966 Jul 18;197(3):191-9.

Iablokova EA, Gorelov AV. Functional disorders of gastrointestinal tract in children: diagnostics and possibilities of spasmolytic therapy. RMJ. 2015;23(21):1263-1267. (in Russian).

Zakharova IN. Regurgitation and vomiting in children: what to do? Consilium medicum]. Pediatriia. Consilium Medicum. 2009;(3):16. (in Russian).

World Gastroenterology Organisation. Probiotics and prebiotics: World Gastroenterology Organisation Global Guidelines. Available from: Accessed: February 2017.

Horvath A, Dziechciarz P, Szajewska H. Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood. Aliment Pharmacol Ther. 2011 Jun;33(12):1302-10. doi: 10.1111/j.1365-2036.2011.04665.x.

Pärtty A, Luoto R, Kalliomäki M, Salminen S, Isolauri E. Effects of early prebiotic and probiotic supplementation on development of gut microbiota and fussing and crying in preterminfants: a randomized, double-blind, placebo-controlled trial. J Pediatr. 2013 Nov;163(5):1272-7.e1-2. doi: 10.1016/j.jpeds.2013.05.035.

Manzoni P, Mostert M, Leonessa ML, et al. Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study. Clin Infect Dis. 2006 Jun 15;42(12):1735-42. doi: 10.1086/504324.

Francavilla R, Miniello V, Magistà AM, et al. A randomized controlled trial of Lactobacillus GG in children with functional abdominal pain. Pediatrics. 2010 Dec;126(6):e1445-52. doi: 10.1542/peds.2010-0467.

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