Effect of ecological factors on manifestation of respiratory diseases

O.S. Kozhyna


For the first time in Ukraine, phase IV of the International Study of Asthma and Allergies in Childhood (ISAAC) program was realized in Kharkiv region in 2015–2017. 6,330 questionnaires were distributed. 6,146 (97 %) schoolchildren took part in the program. 12.8 % of them had respiratory complaints: 13.2 % of children aged 6 to 7 years, 12.4 % — 13 to 14 years old. These results were compared with the data from ISAAC phase I (V.A. Ognev, 1998) to determine the dynamics of respiratory symptoms prevalence: over the last 19 years, the prevalence of respiratory symptoms has decreased by 1.6 times in children of primary school age and by 2 times — in adolescence. The study was conducted in 8 districts of Kharkiv region (Lozivskyi, Kupianskyi, Vovchanskyi, Bohodukhivskyi, Sakhnovshchynskyi, Barvinkivskyi, Derhachivskyi, Novovodolazkyi) which differ by environmental characteristics. In ecologically contaminated areas, the prevalence of wheezing is 1.4 times higher, exercise-induced asthma symptoms — 1.9 times higher and severe dyspnea attacks disturbing night sleep occur 3.4 times more often. The study is intended to improve the bronchial asthma prevention in children population of Kharkiv region.


children; bronchial asthma; prevalence; Kharkiv region; International Study of Asthma and Allergies in Childhood; ecology


World Health Organization. Asthma. Key facts. Available from: Accessed: August 31, 2017.

Barnett SBL, Nurmagambetov TA. Costs of asthma in the United States: 2002-2007. J Allergy Clin Immunol. 2011 Jan;127(1):145-52. doi: 10.1016/j.jaci.2010.10.020.

Umanets TR. Bronchial asthma and allergic rhinitis: way to optimize the compliance and effectiveness of treatment. Asthma and allergy. 2015;(1):61-64. (in Ukranian).

International Study of Asthma and Allergies in Childhood (ISAAC). Available from: Accessed: December, 2012.

Anderson HR, Butland BK, van Donkelaar A, et al. Satellite-based estimates of ambient air pollution and global variations in childhood asthma prevalence. Environ Health Perspect. 2012 Sep;120(9):1333-9. doi: 10.1289/ehp.1104724.

Ognev VA. Epidemiologiia astmy i allergii u detei. Po materialam mezhdunarodnoi programmy po izucheniiu astmy i allergii u detei ISAAC: monografiia [Epidemiology of asthma and allergies in children. Based on materials from the International Program or the Study of Asthma and Allergies in Children ISAAC: monograph]. Kharkiv: Shhedra sadyba pljus; 2015. 337 p. (in Russian).

Asher MI, Stewart AW, Mallol J, et al. Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One. Respir Res. 2010 Jan 21;11:8. doi: 10.1186/1465-9921-11-8.

Baldi I, Tessier JF, Kauffmann F, Jacqmin-Gadda H, Nejjari C, Salamon R. Prevalence of asthma and mean levels of air pollution: results from the French PAARC survey. Pollution Atomosphérique et Affections Respiratoires Chroniques. Eur Respir J. 1999 Jul;14(1):132-8.

Tymchuk AO, Kapusnyk IV, Strebkova AJu, et al, authors; Myhajlychenko TO, editor. Report on the state of the environment in the Kharkiv region in 2016. Kharkiv; 2017. 22-41 pp. (in Ukrainian).

Braun-Fahrländer C, Vuille JC, Sennhauser FH, et al. Respiratory health and long-term exposure to air pollutants in Swiss schoolchildren. SCARPOL Team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution, Climate and Pollen. Am J Respir Crit Care Med. 1997 Mar;155(3):1042-9. doi: 10.1164/ajrccm.155.3.9116984.

Favarato G, Anderson HR, Atkinson R, Fuller G, Mills I, Walton H. Traffic-related pollution and asthma prevalence in children. Quantification of associations with nitrogen dioxide. Air Qual Atmos Health. 2014;7(4):459-466. doi: 10.1007/s11869-014-0265-8.

Shima M, Nitta Y, Ando M, Adachi M. Effects of air pollution on the prevalence and incidence of asthma in children. Arch Environ Health. 2002 Nov-Dec;57(6):529-35. doi: 10.1080/00039890209602084.

Pearce N, Ad-Khaled N, Beasley R, et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2007 Sep;62(9):758-66. doi: 10.1136/thx.2006.070169.

Anderson HR, Ruggles R, Pandey KD, et al. Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC). Occup Environ Med. 2010 May;67(5):293-300. doi: 10.1136/oem.2009.048785.

Copyright (c) 2018 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2020


   Seo анализ сайта