Clinical and epidemiological characteristics of the most common allergy diseases in children

L.V. Duda, Е.N. Оkhotnikova

Abstract


Background. Allergic diseases (bronchial asthma, allergic rhinitis, atopic dermatitis, food allergy, acute urticaria, insect allergy) are disabling life-threatening conditions and are a cause of worldwide concern. Objective: to determine the prevalence of allergy symptoms in children and to evaluate the modern level of allergic diseases diagnosis in our country on the example of Kyiv region. Materials and methods. 1011 children from 4 age groups were surveyed: group I — 305 patients (aged 1 month — 4 years), group II — 254 children (6–7 years), group III — 254 persons (13–14 years), group IV — 198 children (15–17 years). Results. Quite high prevalence of bronchial asthma, allergic rhinitis, atopic dermatitis, food allergy, acute urticaria and insect allergy were received. At the same time, significantly low levels of diagnosing these diseases (e.g. asthma) were revealed. Despite the significant incidence of wheezing (more than 3 times in the past year of life), children from all age ca­tegories have reliably low diagnosis level of asthma (p = 0.000), especially those under 4 years of age. According to received results, the food allergy manifestations (i.e. acute urticaria and angioedema) are being detected more and more often in younger age. Conclusions. The level of diagnosing allergic diseases, particularly asthma, remains low in Ukraine, especially in children under 4 years.


Keywords


allergic diseases; bronchial asthma; allergic rhinitis; atopic dermatitis; food allergy; prevalence; epidemiological characteristics

References


Agafonova IA, Lenkova GV, Khlyzina ET. Epidemiology of allergic diseases in the Dnepropetrovsk region. Novosti Meditsiny i Farmatsii. Allergologiia i immunologiia. 2010:(322). Available from: http://www.mif-ua.com/archive/article/12443. Accessed: August 07, 2010. (in Russian).

Calderon MA, Demoly P, Gerth van Wijk R, et al. EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy. Clin Transl Allergy. 2012 Oct 30;2(1):20. doi: 10.1186/2045-7022-2-20.

Allergic diseases as a problem of worldwide healthcare according to materials of 3rd Ukrainian Allergic Congress. Novosti Meditsiny i Farmatsii. 2011;(387). Available from: http://www.mif-ua.com/archive/article/22745. Accessed: November 18, 2011. (in Ukrainian).

Pawankar R, Canonica GW, Holgate ST, Lockey RF, authors; Sepiashvili RI, Slavianskaia TA, editors. Belaia kniga WAO po allergii 2011–2012: reziume [WAO White Paper on Allergy 2011-2012: summary]. Moscow: Meditsina-Zdorov'e; 2012. 12 p. (in Russian).

European Academy of Allergy and Clinical Immunology (EAACI). Tackling the Allergy Crisis in Europe - Concerted Policy Action Needed: Advocacy Manifesto. Available from: http://www.eaaci.org/images/media/EAACI_Manifesto_brochure_Interactive.pdf. Accessed: April 04, 2016.

The UCB Institute of Allergy. European Allergy White Paper: Allergic Diseases as a Public Health Problem in Europe. Available from: https://www.ucb.com/_up/tuioa_com/images/allergic-tobeornottobe_tcm114-11441.pdf. Accessed: January 20, 2016.

Zaikov SV, Hatska DO, Korytska IV. Incidence of allergic diseases (bronchial asthma, allergic rhinitis, atopic dermatitis) among children and youths in Vinnitsa region (results of 2nd stage of clinic and epidemiologic study). Asthma and allergy. 2015;(3):28-34. (in Ukrainian).

Ohotnikova ON. Bronchial asthma and allergic rhinitis in children under 6 years of age: treatment of comorbid pathology features. Asthma and allergy. 2015;(4):65-67. (in Russian).

Reviakina VA, Filatova TA. From atopic dermatitis to bronchial asthma in children. Lechaschii Vrach. 2006;(1). Available from: https://www.lvrach.ru/2006/01/4533297/. (in Russian). Accessed: January 31, 2006.

Ognev VA. Epidemiologiia astmy i allergii u detei. Po materialam mezhdunarodnoi programmy ISAAC: monografiia [Epidemiology of asthma and allergies in children. Based on ISAAC: monograph]. Kharkiv: Shchedra sadiba plius; 2015. 336 p. (in Russian).

Lasitsa OI, Lasitsa TS. Bronkhial'naia astma v praktike semeinogo vracha [Bronchial asthma in the practice of a family doctor]. Kyiv: ZAO Atlant UMS; 2001. 263 p. (in Russian).

The International Study of Asthma and Allergies in Childhood (ISAAC). Available from: http://isaac.auckland.ac.nz/.

Mohammad S, Montefort S, Ng’ang’a L, et al, authors; Asher M, Strachan D, Pearce N, García-Marcos L, editors. The ISAAC Story: The International Study of Asthma and Allergies in Childhood. Auckland; 2011. 420 p.

Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J. 1995 Mar;8(3):483-91. doi: 10.1183/09031936.95.08030483.

Ellwood P, Asher MI, Billo NE, et al. The Global Asthma Network rationale and methods for Phase I global surveillance: prevalence, severity, management and risk factors. Eur Respir J. 2017 Jan 11;49(1). pii: 1601605. doi: 10.1183/13993003.01605-2016.

Ellwood P, Asher MI, Beasley R, et al. The international study of asthma and allergies in childhood (ISAAC): phase three rationale and methods. Int J Tuberc Lung Dis. 2005 Jan;9(1):10-6.

Weiland SK, Björkstén B, Brunekreef B, et al. Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods. Eur Respir J. 2004 Sep;24(3):406-12. doi: 10.1183/09031936.04.00090303.

Akopian AZ. Etapnost' formirovaniia i rasprostranennost' allergicheskikh zabolevanii u detei g. Kieva po unifitsirovannoi metodike ISAAC. Diss. kand. med. nauk [The gradual formation and prevalence of allergic diseases in children in Kiev under the unified methodology ISAAC. PhD diss.]. Kyiv; 2008. 22 p. (in Ukrainian).

Sokolova LV. Diagnostic errors in bronchial asthma in children. Pul'monologiya. 2002;(1):24-27. (in Russian).

Voronenko JuV, Puhlyk BM, Kuznecova LV, et al, authors; Kuznecova LV, editor. Allergologija: pidruchnyk [Allergology: a textbook]. Kyiv; 2008. 295 p. (in Ukrainian).

Ren CL, Esther CR Jr, Debley JS, et al. Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing. Am J Respir Crit Care Med. 2016 Aug 1;194(3):356-73. doi: 10.1164/rccm.201604-0694ST.

Fedorciv OJe. Prevalence of allergy diseases among children in Ternopil region. Actual problems of pediatry, obstetrics and gynecology. 2013;(2):28-31. (in Ukrainian).

Klymenko VA. Prevention of allergic diseases in young children. Zdorov`ja Ukrai'ny. Pediatrija. 2015;(33):8-9. (in Russian).

Pearce N, Asher I, Billo N, et al. Asthma on the global NCD agenda: a neglected epidemic. Lancet Respir Med. 2013 Apr;1(2):96-8. doi: 10.1016/S2213-2600(13)70023-7.

Paschall VL. Hymenoptera Venom Allergy. Available from: http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/allergy/hymenoptera-venom-allergy/. Accessed: October 16, 2016.

World Health Organization. Global Action Plan for the Prevention and Control of NCDs 2013-2020. Available from: http://www.who.int/nmh/events/ncd_action_plan/en/. Accessed: October 05, 2015.

NIAID-Sponsored Expert Panel, Boyce JA, Assa'ad A, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010 Dec;126(6 Suppl):S1-58. doi: 10.1016/j.jaci.2010.10.007.

Baral VR, Hourihane JO. Food allergy in children. Postgrad Med J. 2005 Nov;81(961):693-701. doi: 10.1136/pgmj.2004.030288.

Chernysh YR, Okhotnikova OM. Clinical manifestations of gastrointestinal form of food allergy in children and approaches to its diagnosis. Zdorovʹe rebenka. 2017;12(5):611-622. doi: 10.22141/2224-0551.12.5.2017.109280. (in Ukrainian).

Burks AW, Tang M, Sicherer S, et al. ICON: food allergy. J Allergy Clin Immunol. 2012 Apr;129(4):906-20. doi: 10.1016/j.jaci.2012.02.001.

National Institute for Health and Care Excellence. Food allergy in under 19s: assessment and diagnosis. Available from: https://www.nice.org.uk/guidance/cg116. Accessed: February 2011.

Tkachenko N. Diagnosis of food allergy in children and adolescents. Recommendations NICE (February 2011). Dytjachyj likar. 2011;(9):77-80. (in Ukrainian).

Alves B, Sheikh A. Age specific aetiology of anaphylaxis. Arch Dis Child. 2001 Oct;85(4):348. doi: 10.1136/adc.85.4.348b.

Bock SA, Munoz-Furlong A, Sampson HA. Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol. 2001 Jan;107(1):191-3. doi: 10.1067/mai.2001.112031.

Clarke AT, Ewan PW. Food allergy in childhood. Arch Dis Child. 2003 Jan;88(1):79-81. doi: 10.1136/adc.88.1.79.

Sheikh A, Alves B. Hospital admissions for acute anaphylaxis: time trend study. BMJ. 2000 May 27;320(7247):1441. doi: 10.1136/bmj.320.7247.1441.

Chernysh YR, Okhotnikova OM. Respiratory manifestations of food allergy in children under 6 years of age. Asthma and allergy. 2016;(1):69-70. (in Ukrainian).

Thong BY, Hourihane JO. Monitoring of IgE-mediated food allergy in childhood. Acta Paediatr. 2004 Jun;93(6):759-64.

Macharadze DSh. Clinical manifestations of food allergy in children and adults. International Journal of Immunopathology, Allergology, Infectology. 2016;(2):35-55. doi: 10.14427/jipai.2016.2.35. (in Russian).

Macharadze DSh. Clinical features of food allergy in children. Pediatriya. 2013;92(3):110-116. (in Russian).

Klymenko VA, Kozhem’jaka AI, Koliushko KH, Karpushenko JuV, Adarjukova LM, Hocenko GO. Peculiarities of nutritional synthesis in children of Kharkiv region. Novosti Meditsiny i Farmatsii. Allergologiia i pul'monologiia. 2011;(380). Available from: http://www.mif-ua.com/archive/article/21209. Accessed: September 13, 2011. (in Ukrainian).

Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JN; EAACI Interest Group on Insect Venom Hypersensitivity. Diagnosis of Hymenoptera venom allergy. Allergy. 2005 Nov;60(11):1339-49. doi: 10.1111/j.1398-9995.2005.00963.x.

Antonicelli A, Bilo MB, Bonifazi F. Epidemiology of Hymenoptera allergy. Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):341-6.

Müller UR. New developments in the diagnosis and treatment of hymenoptera venom allergy. Int Arch Allergy Immunol. 2001 Apr;124(4):447-53. doi: 10.1159/000053779.

Ponochevna OV, Ohotnikova OM. Insect allergy in children. Zdorov`ja Ukrai'ny. Klinichna imunologija. Alergologija. Infektologija. 2017;(99):53-57. (in Ukrainian).

Yavuz ST, Sahiner UM, Buyuktiryaki B, et al. Clinical features of children with venom allergy and risk factors for severe systemic reactions. Int Arch Allergy Immunol. 2013;160(3):313-21. doi: 10.1159/000341666. Epub 2012 Oct 18.

Macharadze DSh. Insect allergy and its therapy aspects. Lechaschii Vrach. 2007;(4). Available from: https://www.lvrach.ru/2007/04/4535026/. Accessed: April 16, 2007. (in Russian).




DOI: https://doi.org/10.22141/2224-0551.13.4.2018.137017

Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2018

 

   Seo анализ сайта