Epidemiology of mite and associated with them food allergies among children population of Rivne region

R.R. Drab, I.V. Guschuk, R.V. Safonov, A.V. Byalkovsky, O.I. Brezetska


Background. Epidemiological instability in the world and country, particularly in Rivne region, is crucial when studying the risk of combined mite and food allergies in children, due to constant changes in environmental factors and increased trigger load, one of the most powerful factors of which are allergens of house dust mites. Consequently, epidemiological monitoring of the features of mite and food allergies mutual influence on immunological mechanisms among children of Rivne region and the environmental factors contamination with house dust mites is urgent. Materials and methods. For the period of 2007–2017, 410 food allergy foci in different age groups were inspected outpatiently and sanitary-parasitologically with the study of acarifauna in them. Results. In samples of house dust from the foci of food and mites allergies, representatives of 8 species of 4 families of allergenic mites were identified; of them, the pathogenic effects of Dermatophagoides pteronyssinus, Dermatophagoides farinae, Acarus siro and Glycyphagus domesticus on sensitization of the children population were determined parasitologically and immunologically. 91 % of children aged 0–3 years have been diagnosed only with food immunoglobulin E (IgE)-mediated allergy, the effect of house dust mites on allergic processes has not been proved. With increasing age of sensitized children, the growth of laboratory-identified IgE-dependent food allergies was observed — from 68 % in the age group of 3–6 years to 88 % in adolescents aged 10–14 years, mostly of polyvalent type. Similarly, from 32 % of children aged 3–6 years to 54 % of patients aged 10–14 years, the role of house dust mites in the formation and maintenance of generalized forms of atopic reactions to mites allergy indications was established and confirmed. Conclusions. The epidemiological situation in children population of Rivne region in terms of food and mite allergies is defined as unstable; a situational analysis of immunological status in children aged 0–14 years regarding mite and food allergies was conducted, and the role of the environmental contamination with house dust mites as factors of a high allergic background has been observed.


epidemiological monitoring; mite allergy; food allergy; sensitization; house dust mite; environment of human life


Cabinet of Ministers of Ukraine. Order № 1002-p dated November 30, 2016. On the approval of the Concept of development of the public health system. Available from: Accessed: November 30, 2016.

Macharadze DSh. Clinical features of food allergy in children. Pediatria. 2013;(3):110-116. (in Russian).

Burks A, Tang M, Sicherer S, et al. ICON: food allergy. J Allergy Clin Immunol. 2012 Apr;129(4):906-20. doi: 10.1016/j.jaci.2012.02.001.

Yurtseva AP, Fofanova OV, Lotovska TV. Сurrent approaches to diagnosis of food allergy in children and basic principles of diet therapy. Problemy klinichnoi' pediatrii'. 2013;3(21):40-45. (in Ukrainian).

Balabolkin II. Food allergy in children: modern aspects of pathogenesis and approaches to therapy and prophylaxis. Immunopathology, Allergology, Infectology. 2013;3:36-46. (in Russian).

Rona RJ, Keil T, Summers C, et al. The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol. 2007 Sep;120(3):638-46. doi: 10.1016/j.jaci.2007.05.026.

Høst A, Halken S. A prospective study of cow milk allergy in Danish infants during the first 3 years of life. Clinical course in relation to clinical and immunological type of hypersensitivity reaction. Allergy. 1990 Nov;45(8):587-96.

Eggesbø M, Botten G, Halvorsen R, Magnus P. The prevalence of allergy to egg: a population-based study in young children. Allergy. 2001 May;56(5):403-11.

Sosnina OB, Balabolkin II, Botvinyeva VV, Filyanskaya YeG. Clinical and immune manifestations of food allergy in adolescents. Rossiiskii Pediatricheskii Zhurnal. 2008;(3):14-17. (in Russian).

Akopian AZ. The prevalence of allergic diseases in Kiev by ISAAC-programm. Imunologija ta alergologija: nauka i praktyka. 1999;(3):11. (in Russian).

Lasitsa OL, Lasitsa TS. Bronkhial'naia astma v praktike semeinogo vracha [Bronchial asthma in the practice of a family doctor]. Kyiv: Atlant UMS; 2001. 262 p. (in Russian).

Dubinina EV. Ecological and faunistic researches of dust mites due to the problem of allergy. In: Parazitologicheskii sbornik Zoologicheskogo instituta AN SSSR. Tom 33 [Parasitological collection of the Zoological Institute of the Academy of Sciences of the USSR. Vol 33]. Leningrad: Nauka; 1985. 209-229 pp. (in Russian).

Stankevich VV, Tarabarova SB. Sanitary-and-hygienic problem of contamination the helminths of objects of environment in Ukraine (review). Gigijena naselenyh misc'. 2015;(66):85-89. (in Ukrainian).

Mochalova AA. Clinical and pathogenetic significance of micronutrient metabolism disorders in parasitic diseases in school-aged children. Aktualʹnaâ Infektologiâ. 2014;1(2):45-47. doi: 10.22141/2312-413x.1.02.2014.82281. (in Russian).

Sagach OS, Gushha GJ, Pavlikovs'ka TM, Lektjeva IM, Ministry of Нealth of Ukraine. MP–2007. Metody vyjavlennja ta vyznachennja klishhiv, jaki zustrichajut'sja u pobutovomu pylu. Metodychni rekomendacii' [MP Methods of detection and identification of ticks that occur in domestic dust. Guidelines]. Kyiv; 2013. 31 p. (in Ukrainian).

Copyright (c) 2018 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2019


   Seo анализ сайта