Priority of using herbal medicines in the treatment of viral respiratory infections in children
Background. Today, more than 80 % of the world population use herbal medicines. They have different therapeutic effects influencing the whole body. The good efficiency and tolerability of drugs containing Pelargonium sidoides is confirmed by clear scientific criteria and clinical trial data. The purpose of our research was to study the clinical efficiency and safety of the herbal medicine Papalor (Pelargonium sidoides) in the treatment of children with acute respiratory viral infections. Materials and methods. The clinical study included 67 boys and 53 girls aged 1 to 12 years. All children were divided into three age groups: 1–2, 3–5 and 6–12 years. Patients of the main group (n = 60) received Papalor, patients of the control group (n = 60) took only symptomatic treatment. The greatest number of children aged 3 to 5 years. Nosological manifestations of acute respiratory viral infections were nasopharyngitis, acute bronchitis and sinusitis. According to the study design, there were three control visits. Results. Analysis of the general criteria of acute respiratory viral infections revealed that the average duration of fever in patients of the main group was 2.7 days, in the control group — 3.4 days, symptoms of intoxication — 2.2 days and 2.9 days, respectively. Catarrhal presentations (runny nose, cough, sore throat) lasted for 4.2 days in patients of the main group, in controls — 4.6 days. More than 60 % of patients in both groups had acute bronchitis. At the beginning of treatment, the average level of Bronchitis Severity Score in both groups was almost the same. Already in 3–5 days, there was a significant difference in favor of the main group (p < 0.001), and by the end of treatment (day 7), it was even more expressed. From the start of therapy to its completion, Bronchitis Severity Score improved by 7.4 ± 1.8 in Pelargonium sidoides group compared with 5.2 ± 1.7 in the control group. Conclusions. A clinical study of Papalor effectiveness in the treatment of acute respiratory viral infections in children has shown reliable clinical results. The pronounced antiviral, moderate bacteriostatic effects, as well as mucociliary and anti-inflammatory properties of Papalor allowed using it both in comprehensive treatment and as a monotherapy.
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