Development of the immune response in pneumonia due to Staphylococcus aureus (part 7)

A.E. Abaturov, A.A. Nikulinа

Abstract


The article on the basis of literature data demonstrates the role of cellular reactions in the development of the immune response in pneumonia caused by Staphylococcus aureus. Тhe report describes mechanisms of interaction between Staphylococcus aureus and innate lymphoid cells, ­T-lymphocytes. The article compares NK-cells receptor systems and describes mechanisms of infected cell killing by the innate immune cells.

Keywords


pneumonia; immune response; Staphylococcus aureus; T-lymphocytes; NK-cells

References


Ahn YO, Weeres MA, Neulen ML, et al. Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation. Eur J Immunol. 2015 Aug;45(8):2335-42. doi: 10.1002/eji.201445213.

Archer NK, Adappa ND, Palmer JN, et al. Interleukin-17A (IL-17A) and IL-17F Are Critical for Antimicrobial Peptide Production and Clearance of Staphylococcus aureus Nasal Colonization. Infect Immun. 2016 Nov 18;84(12):3575-3583. doi: 10.1128/IAI.00596-16.

Aron JL, Akbari O. Regulatory T cells and type 2 innate lymphoid cell-dependent asthma. Allergy. 2017 Feb 4. doi: 10.1111/all.13139.

Attaf M, Legut M, Cole DK, Sewell AK. The T cell antigen receptor: the Swiss army knife of the immune system. Clin Exp Immunol. 2015 Jul;181(1):1-18. doi: 10.1111/cei.12622.

Bekeredjian-Ding I, Stein C, Uebele J. The Innate Immune Response Against Staphylococcus aureus. Curr Top Microbiol Immunol. 2015 Dec 15. doi: 10.1007/82_2015_5004.

Berzins SP, Smyth MJ, Baxter AG. Presumed guilty: natural killer T cell defects and human disease. Nat Rev Immunol. 2011 Feb;11(2):131-42. doi: 10.1038/nri2904.

Birkholz AM, Kronenberg M. Antigen specificity of invariant natural killer T-cells. Biomed J. 2015 Dec;38(6):470-83. doi: 10.1016/j.bj.2016.01.003.

Born WK, Kemal Aydintug M, O'Brien RL. Diversity of γδ T-cell antigens. Cell Mol Immunol. 2013 Jan;10(1):13-20. doi: 10.1038/cmi.2012.45.

Brennan PJ, Brigl M, Brenner MB. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nat Rev Immunol. 2013 Feb;13(2):101-17. doi: 10.1038/nri3369.

Brigl M, Brenner MB. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Semin Immunol. 2010 Apr;22(2):79-86. doi: 10.1016/j.smim.2009.10.006.

Buechel HM, Stradner MH, D'Cruz LM. Stages versus subsets: Invariant Natural Killer T cell lineage differentiation. Cytokine. 2015 Apr;72(2):204-9. doi: 10.1016/j.cyto.2014.12.005.

Chandra S, Kronenberg M. Activation and Function of iNKT and MAIT Cells. Adv Immunol. 2015;127:145-201. doi: 10.1016/bs.ai.2015.03.003.

Cheng H, Jin C, Wu J, Zhu S, Liu YJ, Chen J. Guards at the gate: physiological and pathological roles of tissue-resident innate lymphoid cells in the lung. Protein Cell. 2017 Dec;8(12):878–895. doi: 10.1007/s13238-017-0379-5.

Cheng M, Qian L, Shen G, et al. Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanism. Cancer Res. 2014 Aug 1;74(15):4030-41. doi: 10.1158/0008-5472.CAN-13-2462.

Cheng P, Liu T, Zhou WY, et al. Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia. BMC Immunol. 2012 Jul 9;13:38. doi: 10.1186/1471-2172-13-38.

Cording S, Medvedovic J, Cherrier M, Eberl G. Development and regulation of RORγt(+) innate lymphoid cells. FEBS Lett. 2014 Nov 17;588(22):4176-81. doi: 10.1016/j.febslet.2014.03.034.

Cortez VS, Colonna M. Diversity and function of group 1 innate lymphoid cells. Immunol Lett. 2016 Nov;179:19-24. doi: 10.1016/j.imlet.2016.07.005.

Cowley SC. MAIT cells and pathogen defense. Cell Mol Life Sci. 2014 Dec;71(24):4831-40. doi: 10.1007/s00018-014-1708-y.

Crosby CM, Kronenberg M. Invariant natural killer T cells: front line fighters in the war against pathogenic microbes. Immunogenetics. 2016 Aug;68(8):639-48. doi: 10.1007/s00251-016-0933-y.

Cua DJ, Tato CM. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol. 2010 Jul;10(7):479-89. doi: 10.1038/nri2800.

Dhodapkar MV, Kumar V. Type II NKT Cells and Their Emerging Role in Health and Disease. J Immunol. 2017 Feb 1;198(3):1015-1021. doi: 10.4049/jimmunol.1601399.

Dieli F, Sireci G, Russo D, et al. Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction. J Exp Med. 2000 Dec 4;192(11):1645-52. PMID: 11104806.

Dudal S, Turriere C, Bessoles S, et al. Release of LL-37 by activated human Vγ9Vδ2 T cells: a microbicidal weapon against Brucella suis. J Immunol. 2006 Oct 15;177(8):5533-9. doi: 10.4049/jimmunol.177.8.5533.

Eckle SB, Corbett AJ, Keller AN, et al. Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells. J Biol Chem. 2015 Dec 18;290(51):30204-11. doi: 10.1074/jbc.R115.685990.

Espinosa E, Belmant C, Pont F, et al. Chemical synthesis and biological activity of bromohydrin pyrophosphate, a potent stimulator of human gamma delta T cells. J Biol Chem. 2001 May 25;276(21):18337-44. doi: 10.1074/jbc.M100495200.

Franciszkiewicz K, Salou M, Legoux F, et al. MHC class I-related molecule, MR1, and mucosal-associated invariant T cells. Immunol Rev. 2016 Jul;272(1):120-38. doi: 10.1111/imr.12423.

Fraser JD, Proft T. The bacterial superantigen and superantigen-like proteins. Immunol Rev. 2008 Oct;225:226-43. doi: 10.1111/j.1600-065X.2008.00681.x.

Gao Y, Williaм AP. Role of Innate T Cells in Anti-Bacterial Immunity. Front Immunol. 2015 Jun 11;6:302. doi: 10.3389/fimmu.2015.00302.

Georgel P, Radosavljevic M, Macquin C, Bahram S. The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice. Mol Immunol. 2011 Feb;48(5):769-75. doi: 10.1016/j.molimm.2010.12.002.

Gober HJ, Kistowska M, Angman L, Jenö P, Mori L, De Libero G. Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med. 2003 Jan 20;197(2):163-8. doi: 10.1084/jem.20021500.

Hao J, Wu X, Xia S, et al. Current progress in γδ T-cell biology. Cell Mol Immunol. 2010 Nov;7(6):409-13. doi: 10.1038/cmi.2010.50.

Harly C, Guillaume Y, Nedellec S, et al. Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset. Blood. 2012 Sep 13;120(11):2269-79. doi: 10.1182/blood-2012-05-430470.

Hayworth JL, Mazzuca DM, Maleki Vareki S, Welch I, McCormick JK, Haeryfar SM. CD1d-independent activation of mouse and human iNKT cells by bacterial superantigens. Immunol Cell Biol. 2012 Aug;90(7):699-709. doi: 10.1038/icb.2011.90.

Hazenberg MD, Spits H. Human innate lymphoid cells. Blood. 2014 Jul 31;124(5):700-9. doi: 10.1182/blood-2013-11-427781.

Hinks TS. Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease. Immunology. 2016 May;148(1):1-12. doi: 10.1111/imm.12582.

Hu CK, Venet F, Heffernan DS, et al. The role of hepatic invariant NKT cells in systemic/local inflammation and mortality during polymicrobial septic shock. J Immunol. 2009 Feb 15;182(4):2467-75. doi: 10.4049/jimmunol.0801463.

Ivanov S, Paget C, Trottein F. Role of non-conventional T lymphocytes in respiratory infections: the case of the pneumococcus. PLoS Pathog. 2014 Oct 9;10(10):e1004300. doi: 10.1371/journal.ppat.1004300.

Jiao Y, Huntington ND, Belz GT, Seillet C. Type 1 Innate Lymphoid Cell Biology: Lessons Learnt from Natural Killer Cells. Front Immunol. 2016 Oct 12;7:426. doi: 10.3389/fimmu.2016.00426.

Johansson MA, Björkander S, Mata Forsberg M, et al. Probiotic Lactobacilli Modulate Staphylococcus aureus-Induced Activation of Conventional a Unconventional T cells and NK Cells. Front Immunol. 2016 Jul 11;7:273. doi: 10.3389/fimmu.2016.00273.

Kalyan S, Kabelitz D. Defining the nature of human γδ T cells: a biographical sketch of the highly empathetic. Cell Mol Immunol. 2013 Jan;10(1):21-9. doi: 10.1038/cmi.2012.44.

Kirby AC, Newton DJ, Carding SR, Kaye PM. Evidence for the involvement of lung-specific gammadelta T cell subsets in local responses to Streptococcus pneumoniae infection. Eur J Immunol. 2007 Dec;37(12):3404-13. doi: 10.1002/eji.200737216.

Kirby AC, Newton DJ, Carding SR, Kaye PM. Pulmonary dendritic cells and alveolar macrophages are regulated by gammadelta T cells during the resolution of S. pneumoniae-induced inflammation. J Pathol. 2007 May;212(1):29-37. doi: 10.1002/path.2149.

Kohlgruber AC, Donado CA, LaMarche NM, Brenner MB, Brennan PJ. Activation strategies for invariant natural killer T cells. Immunogenetics. 2016 Aug;68(8):649-63. doi: 10.1007/s00251-016-0944-8.

Kumar V, Delovitch TL. Different subsets of natural killer T cells may vary in their roles in health and disease. Immunology. 2014 Jul;142(3):321-36. doi: 10.1111/imm.12247.

Kurioka A, Ussher JE, Cosgrove C, et al. MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets. Mucosal Immunol. 2015 Mar;8(2):429-40. doi: 10.1038/mi.2014.81.

Kwiecinski J, Rhost S, Löfbom L, et al. Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway. Infect Immun. 2013 Apr;81(4):1114-20. doi: 10.1128/IAI.01334-12.

Le Bourhis L, Dusseaux M, Bohineust A, et al. MAIT cells detect and efficiently lyse bacterially-infected epithelial cells. PLoS Pathog. 2013;9(10):e1003681. doi: 10.1371/journal.ppat.1003681.

Le Bourhis L, Martin E, Péguillet I, et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat Immunol. 2010 Aug;11(8):701-8. doi: 10.1038/ni.1890.

Marashian SM, Mortaz E, Jamaati HR, et al. Role of Innate Lymphoid Cells in Lung Disease. Iran J Allergy Asthma Immunol. 2015 Aug;14(4):346-60. PMID: 26547702.

Marischen L, Wesch D, Schröder JM, Wiedow O, Kabelitz D. Human gammadelta T cells produce the protease inhibitor and antimicrobial peptide elafin. Scand J Immunol. 2009 Dec;70(6):547-52. doi: 10.1111/j.1365-3083.2009.02337.x.

Mathews JA, Kasahara DI, Ribeiro L, Wurmbrand AP, Ninin FM, Shore SA. γδ T Cells Are Required for M2 Macrophage Polarization and Resolution of Ozone-I uced Pulmonary Inflammation in Mice. PLoS One. 2015 Jul 2;10(7):e0131236. doi: 10.1371/journal.pone.0131236.

McAleer JP, Kolls JK. Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense. Immunol Rev. 2014 Jul;260(1):129-44. doi: 10.1111/imr.12183.

Meierovics A, Yankelevich WJ, Cowley SC. MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3119-28. doi: 10.1073/pnas.1302799110.

Meierovics AI, Cowley SC. MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection. J Exp Med. 2016 Nov 14;213(12):2793-2809. doi: 10.1084/jem.20160637.

Melo-Gonzalez F, Hepworth MR. Functional and phenotypic heterogeneity of group 3 innate lymphoid cells. Immunology. 2017 Mar;150(3):265-275. doi: 10.1111/imm.12697.

Mjösberg J, Spits H. Human innate lymphoid cells. J Allergy Clin Immunol. 2016 Nov;138(5):1265-1276. doi: 10.1016/j.jaci.2016.09.009.

Nada MH, Wang H, Workalemahu G, Tanaka Y, Morita CT. Enhancing adoptive cancer immunotherapy with Vγ2Vδ2 T cells through pulse zoledronate stimulation. J Immunother Cancer. 2017 Feb 21;5:9. doi: 10.1186/s40425-017-0209-6.

Nakasone C, Yamamoto N, Nakamatsu M, et al. Accumulation of gamma/delta T cells in the lungs and their roles in neutrophil-mediated host defense against pneumococcal infection. Microbes Infect. 2007 Mar;9(3):251-8. doi: 10.1016/j.micinf.2006.11.015.

Parkinson RM, Collins SL, Horton MR, Powell JD. Egr3 induces a Th17 response by promoting the development of γδ T cells. PLoS One. 2014 Jan 24;9(1):e87265. doi: 10.1371/journal.pone.0087265.

Paul S, Singh AK, Shilpi, Lal G. Phenotypic and functional plasticity of gamma-delta (γδ) T cells in inflammation and tolerance. Int Rev Immunol. 2014 Nov-Dec;33(6):537-58. doi: 10.3109/08830185.2013.863306.

Rahimpour A, Koay HF, Enders A, et al. Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers. J Exp Med. 2015 Jun 29;212(7):1095-108. doi: 10.1084/jem.20142110.

Rampuria P, Lang ML. CD1d-dependent expansion of NKT follicular helper cells in vivo and in vitro is a product of cellular proliferation and differentiation. Int Immunol. 2015 May;27(5):253-63. doi: 10.1093/intimm/dxv007.

Robinette ML, Colonna M. Immune modules shared by innate lymphoid cells and T cells. J Allergy Clin Immunol. 2016 Nov;138(5):1243-1251. doi: 10.1016/j.jaci.2016.09.006.

Rossjohn J, Pellicci DG, Patel O, Gapin L, Godfrey DI. Recognition of CD1d-restricted antigens by natural killer T cells. Nat Rev Immunol. 2012 Dec;12(12):845-57. doi: 10.1038/nri3328.

Salio M, Silk JD, Jones EY, Cerundolo V. Biology of CD1- and MR1-restricted T cells. Annu Rev Immunol. 2014;32:323-66. doi: 10.1146/annurev-immunol-032713-120243.

Scanlon ST, Thomas SY, Ferreira CM, et al. Airborne lipid antigens mobilize resident intravascular NKT cells to induce allergic airway inflammation. J Exp Med. 2011 Sep 26;208(10):2113-24. doi: 10.1084/jem.20110522.

Seyda M, Elkhal A, Quante M, Falk CS, Tullius SG. T Cells Going Innate. Trends Immunol. 2016 Aug;37(8):546-56. doi: 10.1016/j.it.2016.06.004.

Silver JS, Kearley J, Copenhaver AM, et al. Erratum: Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nat Immunol. 2016 Jul 19;17(8):1005. doi: 10.1038/ni0816-1005c.

Silver JS, Kearley J, Copenhaver AM, et al. Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs. Nat Immunol. Jun;17(6):626-35. doi: 10.1038/ni.3443.

Small CL, McCormick S, Gill N, et al. NK cells play a critical protective role in host defense against acute extracellular Staphylococcus aureus bacterial infection in the lung. J Immunol. Apr 15;180(8):5558-68. doi: 10.4049/jimmunol.180.8.5558.

Svedova J, Tsurutani N, Liu W, Khanna KM, Vella AT. TNF and CD28 Signaling Play Unique but Complementary Roles in the Systemic Recruitment of Innate Immune Cells after Staphylococcus aureus Enterotoxin A Inhalation. J Immunol. 2016 Jun 1;196(11):4510-21. doi: 10.4049/jimmunol.1600113.

Tebartz C, Horst SA, Sparwasser T, et al. A major role for myeloid-derived suppressor cells and a minor role for regulatory T cells in immunosuppression during Staphylococcus aureus infection. J Immunol. 2015 Feb 1;194(3):1100-11. doi: 10.4049/jimmunol.1400196.

Turchinovich G, Hayday AC. Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells. Immunity. 2011 Jul 22;35(1):59-68. doi: 10.1016/j.immuni.2011.04.018.

Murakami T, Hatano S, Yamada H Iwakura Y, Yoshikai Y. Two Types of Interleukin 17A-Producing γδ T Cells in Protection Against Pulmonary Infection With Klebsiella pneumonia. J Infect Dis. 2016 Dec 1;214(11):1752-1761. doi: 10.1093/infdis/jiw443.

Uldrich AP, Le Nours J, Pellicci DG, et al. CD1d-lipid antigen recognition by the γδ TCR. Nat Immunol. 2013 Nov;14(11):1137-45. doi: 10.1038/ni.2713.

Van Maele L, Carnoy C, Cayet D, et al. Activation of Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection. J Infect Dis. 2014 Aug 1;210(3):493-503. doi: 10.1093/infdis/jiu106.

Vavassori S, Kumar A, Wan GS, et al. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells. Nat Immunol. 2013 Sep;14(9):908-16. doi: 10.1038/ni.2665.

von Köckritz-Blickwede M, Rohde M, Oehmcke S, et al. Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model. Am J Pathol. 2008 Dec;173(6):1657-68. doi: 10.2353/ajpath.2008.080337.

Wands JM, Roark CL, Aydintug MK, et al. Distribution and leukocyte contacts of gammadelta T cells in the lung. J Leukoc Biol. 2005 Nov;78(5):1086-96. doi: 10.1189/jlb.0505244.

Wang H, Morita CT. Sensor Function for Butyrophilin 3A1 in Prenyl Pyrophosphate Stimulation of human Vγ2Vδ2 T Cells. J Immunol. 2015 Nov 15;195(10):4583-94. doi: 10.4049/jimmunol.1500314.

Wingender G, Sag D, Kronenberg M. NKT10 cells: a novel iNKT cell subset. Oncotarget. 2015 Sep 29;6(29):26552-3. doi: 10.18632/oncotarget.5270.

Wong EB, Ndung'u T, Kasprowicz VO. The role of mucosal-associated invariant T cells in infectious diseases. Immunology. 2017 Jan;150(1):45-54. doi: 10.1111/imm.12673.

Zhao H, Li W, Gao Y, Li J, Wang H. Exposure to particular matter increases susceptibility to respiratory Staphylococcus aureus infection in rats via reducing pulmonary natural killer cells. Toxicology. 2014 Nov 5;325:180-8. doi: 10.1016/j.tox.2014.09.006.

Ziegler C, Goldmann O, Hobeika E, Geffers R, Peters G, Medina E. The dynamics of T cells during persistent Staphylococcus aureus infection: from antigen-reactivity to in vivo anergy. EMBO Mol Med. 2011 Nov;3(11):652-66. doi: 10.1002/emmm.201100173.




DOI: https://doi.org/10.22141/2224-0551.12.8.2017.119257

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