DOI: https://doi.org/10.22141/2224-0551.12.8.2017.119249

World experience on the diagnosis of interstitial diseases of the lungs in children (up-date 2017)

M.O. Gonchar, O.L. Logvinova

Abstract


The article presents modern principles of classification, diagnosis and treatment of interstitial lungs diseases in children for the practice of pediatricians, family doctors, pediatric pulmonologists, thoracic surgeons, transplantologists. Interstitial lung diseases are part of the structure of diffuse parenchymal diseases of the lungs, which today includes more than 80 nosological forms. Objective examination, physical development, pulse oxi­metry, chest radiography, high resolution computed tomography, echocardiography, genetic testing of bronchoalveolar lavage and pulmonary biopsy are important for the diagnosis of interstitial lung disease in a child. A modern algorithm recommended by the American Thoracic Society for the diagnosis of interstitial lung disease in a child depends on the age, family and personal history of diffuse parenchymal lung disease. The article defines differential diagnostic approaches to the detection of dise­ases from the group of diffuse parenchymal diseases of the lungs.

Keywords


children; interstitial lung disease; parenchymal lung disease; diagnosis; treatment

References


Avital A, Hevroni A, Godfrey S, et al. Natural history of five children with surfactant protein C mutations and interstitial lung disease. Pediatr Pulmonol. 2014 Nov;49(11):1097-105. doi: 10.1002/ppul.22971.

Brody AS, Guillerman RP. Don‘t let radiation scare trump patient care: 10 ways you can harm your patients by fear of radiation-induced cancer from diagnostic imaging. Thorax. 2014 Aug;69(8):782-4. doi: 10.1136/thoraxjnl-2014-205499.

Bush A, Anthony G, Barbato A, et al. Research in progress: Put the orphanage out of business. Thorax. 2013 Oct;68(10):971-3. doi: 10.1136/thoraxjnl-2012-203201.

Bush A, Cunningham S, de Blic J, et al. European protocols for the diagnosis and initial treatment of interstitial lung disease in children. Thorax. 2015 Nov;70(11):1078-84. doi: 10.1136/thoraxjnl-2015-207349.

Camelo A, Dunmore R, Sleeman MA, Clarke DL. The epithelium in idiopathic pulmonary fibrosis: breaking the barrier. Front Pharmacol. 2014 Jan 10;4:173. doi: 10.3389/fphar.2013.00173.

Deutsch GH, Young LR, Deterding RR, et al. Diffuse lung disease in young children: application of a novel classification scheme. Am J Respir Crit Care Med. 2007 Dec 1;176(11):1120-8. doi: 10.1164/rccm.200703-393OC.

El-Saied MM, Saad K, Hamed EA, et al. Plasma levels of transforming growth factor-B1 connective tissue growth factor; soluble factor related apoptosis and urinary levels of desmosine in childhood interstitial lung diseases. Assiut Med J. 2016;40: 89-102.

Hime NJ, Zurynski Y, Fitzgerald D, et al. Childhood interstitial lung disease: A systematic review. Pediatr Pulmonol. 2015 Dec;50(12):1383-92. doi: 10.1002/ppul.23183.

Kropski JA, Lawson WE, Young LR, et al. Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Dis Model Mech. 2013 Jan;6(1):9-17. doi: 10.1242/dmm.010736.

Kuo CS, Young LR. Interstitial lung disease in children. Curr Opin Pediatr. 2014 Jun;26(3):320-7. doi: 10.1097/MOP.0000000000000094.

Kurland G, Deterding RR, Hagood JS, et al. An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy. Am J Respir Crit Care Med. 2013 Aug 1;188(3):376-94. doi: 10.1164/rccm.201305-0923ST.

Steele MP, Schwartz DA. Molecular mechanisms in progressive idiopathic pulmonary fibrosis. Annu Rev Med. 2013;64:265-76. doi: 10.1146/annurev-med-042711-142004.

Wambach JA, Casey AM, Fishman MP, et al. Genotype-phenotype correlations for infants and children with ABCA3 deficiency. Am J Respir Crit Care Med. 2014 Jun 15;189(12):1538-43. doi: 10.1164/rccm.201402-0342OC.

Wuyts WA, Dooms C, Verleden GM. The clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med. 2013 Apr 1;187(7):777. doi: 10.1164/ajrccm.187.7.777.

Zimmermann GS, von Wulffen W, Huppmann P, et al. Haemodynamic changes in pulmonary hypertension in patients with interstitial lung disease treated with PDE–5 inhibitors. Respirology. 2014 Jul;19(5):700-6. doi: 10.1111/resp.12294.




Copyright (c) 2017 Zdorov'ye Rebenka - Child`s Health

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

 

© Publishing House Zaslavsky, 1997-2018

 

   Seo анализ сайта