Microelements concentration in patients with paroxysmal autonomic failure on the background of thyroid pathology
Background. It is relevant to study the changes in the microelement concentration and its correlation with physical state in patients with paroxysmal autonomic failure (PAF) on the background of thyroid gland pathology. Materials and methods. The research included 44 patients aged from 7 to 17 (14.06 ± 0.18) years old with PAF. All patients were completely examined using clinical and instrumental methods. The composition of macro- and microelements in the blood plasma and the hair root zone was studied by measuring mass fraction of chemical elements in the hair and plasma using X-ray fluorescence method with the help of portable energy-dispersive X-ray fluorescence spectrometer ElvaX; children’s individual microelement profile deviations were also evaluated. Results. In 100 % of patients with PAF, iodine deficiency was found after determination of microelement content in the hair that indicates the necessity of iodine deficiency prevention in such patients. Conclusions. The correlation between the microelements involved in thyroid gland functioning has been established, as well as their content in the hair and blood plasma that indicates a significant microelement imbalance in patients with PAF and requires appropriate correction.
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Kaznacheev KS, Cheganova YuV, Kaznacheeva LF. State of health of the children of early age depending on the element status. Vestnik Novosibirskogo gosudarstvennogo universiteta. Seriia: Biologiia, klinicheskaia meditsina. 2013;11(1):225-230. (in Russian).
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