Evaluating the quality of life in children with gastroesophagel reflux disease

I.M. Nesinа


Background. The purpose of the study was the assessment of the quality of life in adolescents with gastroesophageal reflux disease (GERD) during the treatment. Materials and methods. 49 children aged 13–17 years with gastroesophageal reflux disease were examined. The comparison group consisted of 40 apparently healthy children of the same age. The effectiveness of therapy was evaluated during the treatment and in catamnesis, three months later. Quality of life was assessed using the PedsQL 4.0 inventory adapted for children aged 13 to 18 years, and GSRS — a specialized questionnaire for patients with digestive system diseases. Results. It was found that during the exacerbation of GERD, PedsQL 4.0 scores for all scales of the quality of life, especially psychophysiological features in children, reduced significantly by parent’s estimations. According to the GSRS questionnaire, a positive clinical effect was observed after the treatment, but the analysis of the PedsQL 4.0 inventory scales showed that the rates remained significantly lower compared to the control group. Only after 3 months, there was a positive trend toward increasing the number of points according to all the criteria of the PedsQL 4.0 inventory, which described improvements in the quality of teenager’s lives. Conclusions. The study of the quality of life parameters in the period of GERD clinical remission is a necessary component of treatment and the main criterion for assessing the state in adolescents. It allow to determine the clinical effectiveness and time of the main course of therapy, as well as to predict further course of the disease.


gastroesophageal reflux disease; children; quality of life; quality of life inventory PedsQL-4; special questionnaire GSRS


Shadrіn OG, Іgnatko LV. Current approaches to diagnosis and treatment of gastroesophageal reflux disease in children. Zdorov’ja Ukraїni. 2016;3(41):26-7. (In Ukrainian).

Marushko JuV, Asonov AO. Experoence of pantoprazol usage in complex therapy of intestinal diseases in various age groups. Lіki Ukrajini. 2017;3(209):19-23. (In Ukrainian).

Kriuchko TO, Nesіna ІM, Poda OA, Kolenko ІO. Optimization of treatment protocol in children with gastroesophageal reflux disease. Zdorov'ye Rebenka. 2016;2(70):23-8. (In Ukrainian). doi: 10.22141/2224-0551.2.70.2016.73793.

Abaturov AE, Gerasimenko ON, Zavgorodnja NJu. Hronicheskie CagA (+) Helicobacter pylori-associirovannye gastrity u detej [Chronic gastritis in children associated with CagA(+)Helicobacter pylori. Harkiv: S.A.M.; 2014. 400 p. (In Russian).

Skripnik І. M. diseases with various masks: doctor’s tactics in complicated clinical cases of GERD. Zdorov'ja Ukrajini. 2007;23(180):1-2. (In Ukrainian).

Novik AA, Ionova TI. Rukovodstvo po issledovaniju kachestva zhizni v medicine [Guidelines on study quality of life in medicine]. 2nd ed. Moscow: ZAO OLMA Media Grupp; 2007. 320 p. (In Russian).

Baranov AA, Al'bickij VJu., Valiullina SA, et al. Metody opredelenija i pokazateli kachestva zhizni detej podrostkovogo vozrasta. Posobie dlja vrachej [Methods for determining and parameters of quality of life in adolescents]. Moscow; 2005. 30 p. (In Russian).

Varny JW, Burwinkle TM, Seid M. The PedsQl-4 as a school population health measure: feasibility, reliability, and validity. Qual Life Res. 2006;15(2):203-15. doi: 10.1007/s11136-005-1388-z.

Varni J, Seid M, Kurtin P. The PedsQL™ 4.0 Measurement model for the Pediatric Quality of Life Inventory Version 4.0. Quality of life News Letter. 1997;3:4-10.

Varni J, Seid M, Kurtin P. The PedsQL™ 4.0: Reliability and valid9 ity of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales in healthy and patient populations. Med. Care. 2001;39(8):800-12. PMID: 10024117.

Svedlund J, Sjödin I, Dotevall G. GSRS — a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci. 1988;33(2):129-34. PMID: 3123181.

Copyright (c) 2017 CHILD`S HEALTH

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.


© Publishing House Zaslavsky, 1997-2020


   Seo анализ сайта