Herpes virus 6 hepatitis in an infant

L.A. Khodak, V.I. Brailko, L.V. Mushenko


The article presents a clinical observation of 1-year old child diagnosed with hepatitis in the structure of reactivated form of herpes virus type 6 infection. There was a significant increase in transaminase level with other normal biochemical parameters of the liver. The effect of the administration of antiviral therapy with acyclovir intravenously was obtained.


human herpes virus type 6; children; hepatitis


Volchkova EV, Pak SG, Umbetova KT, et al. Liver involvement in various infectious diseases. Farmateka. 2013;2:11-21. (In Russian).

Cisneros-Herreros JM, Herrero-Romero M. Hepatitis due to herpes group viruses. Enferm Infecc Microbiol Clin. 2006;24(6):392-7. doi: 10.1157/13089695.

Smirnov AV, Chuelov SB, Bryusova IB, Volkova GI. Treatment of Chronic Herpesvirus Hepatitises. Detskie infekcii. 2012;2:31-4. (In Russian).

Gallegos-Orozco JF, Rakela-Brödner J. Hepatitis viruses: not always what it seems to be. Rev Med Chil. 2010;138(10):1302-11. PMID: 21279280. doi: /S0034-98872010001100016.

Mamaeva VA, Goryacheva LG, Rogozina NV. Liver lesions in viral infections. Infektsionnye bolezni. 2014;12(1):52-8. (In Russian).

Shaapuni AR, Mkhitaryan AL. Nature of hepatitis in infectious mononucleosis in patients of different age with typical and subclinical signs of the disease. Aktual'naia infektologiia. 2013;1(1):25-8. (In Russian).

Soo In Yang, Jwa Hye Geong, Jae Young Kim. Clinical characteristics of primary Epstein Barr virus hepatitis with elevation of alkaline phosphatase and γ-glutamyltransferase in children. Yonsei Med J. 2014;55(1):107-12. doi: 10.3349/ymj.2014.55.1.107.

Lee SO, Razonable RR. Current concepts on cytomegalovirus infection after liver transplantation. World J Hepatol. 2010;2:325-336. PMID: 21161017. doi: 10.4254/wjh.v2.i9.325.

Chevret L, Boutolleau D, Halimi-Idri N, et al. Human herpesvirus-6 infection: a prospective study evaluating HHV-6 DNA levels in liver from children with acute liver failure. J Med Virol. 2008 Jun;80(6):1051-7. doi: 10.1002/jmv.21143.

Grima P, Chiavaroli R, Calabrese P, Tundo P, Grima P. Severe hepatitis with autoimmune features following a HHV-6: a case report. Cases J. 2008;1:110. doi: 10.1186/1757-1626-1-110.

Anokhin VA, Sabitova AM. Infections caused by herpes virus type 6: modern features. Rossiiskii vestnik perinatologii i pediatrii. 2016;5:127-31. (In Russian).

Agut H, Bonnafous P, Gautheret-Dejean A. Laboratory and clinical aspects of human herpesvirus 6 infections. Clin Microbiol Rev. 2015;28(2):313-35. doi: 10.1128/CMR.00122-14.

Wolz MM, Sciallis GF, Pittelkow MR. Human herpesviruses 6, 7, and 8 from a dermatologic perspective. Mayo Clin Proc. 2012;87(10):1004-14. PMID: 22819486.  doi: 10.1016/j.mayocp.2012.04.010.

Demidova MV, Kravchenko LV, Levkovich MA, Afonin AA. Current state of herpes virus type 6 in children. Detskie infekcii. 2013;12(3):20-3. doi: 10.22627/2072-8107-2013-12-3-20-23. (In Russian).

Vashura LV, Savenkova MS, Zavadenko NN, et al. Convulsive disorder in children: the role of herpes virus infections. Detskie infekcii. 2014;13(2):48-52. doi: 10.22627/2072-8107-2014-13-2-48-52. (In Russian).

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