DOI: https://doi.org/10.22141/2224-0551.0.2.37.2012.100541

Polymorphism of Interleukin-1β Gene in Children of Chernivtsi Region And its Impact on Development of Duodenal Ulcer

S.V. Sokolnyk

Abstract


There were determined the genotype distribution frequency of interleukin-1β gene gene in promotor region -511C/T. It was defined that interleukin-1β-511*C allele and interleukin-1β-511С/C genotype increase the risk of duodenal ulcer in children, associated with Helicobacter pylori, and interleukin-1β-511*T allele and interleukin-1β-511С/Т genotype reduces the probability of formation of the disease.

Keywords


children, gene polymorphism, interleukin-1β, duodenal ulcer

References


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